[两种含有桉叶油和松针油制剂的局部耐受性]
[Local tolerability of two preparations with eucalyptus oil and pine-needle oil].
作者信息
Willms R U, Funk P, Walther C
机构信息
Praxis für Dermatologie und Venerologie, Magdeburg.
出版信息
MMW Fortschr Med. 2005 Oct 6;147 Suppl 3:109-12.
UNLABELLED
The objective of this open-label, single-centre study was to assess the tolerability of two locally applicable eucalyptus oil and pine-needle oil preparations using patch testing as an accepted and standardised method.
METHOD
Two eucalyptus oil and pine-needle oil preparations were applied to the forearm of 46 subjects with healthy skin using standardised patches. The patches were removed after 48 hours and skin reactions were assessed immediately and after 24 and 48 hours. The major objective was the reaction of the patch test.
RESULT
Neither preparation caused any positive skin reaction in any of the subjects.
CONCLUSION
Skin tolerability to the two eucalyptus oil and pine-needle oil preparations is very good with regard to their active ingredients and other excipients.
未标注
本开放标签、单中心研究的目的是使用斑贴试验这一公认的标准化方法，评估两种局部应用的桉叶油和松针油制剂的耐受性。
方法
使用标准化贴片，将两种桉叶油和松针油制剂应用于46名皮肤健康受试者的前臂。48小时后取下贴片，并在取下后立即、24小时和48小时评估皮肤反应。主要观察指标为斑贴试验的反应。
结果
两种制剂在任何受试者中均未引起任何阳性皮肤反应。
结论
就其活性成分和其他辅料而言，两种桉叶油和松针油制剂的皮肤耐受性非常好。
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