姑息性放疗后喉卡波西肉瘤长期完全缓解
Long-term complete remission of laryngeal Kaposi's sarcoma after palliative radiotherapy.
作者信息
Ares Carmen, Allal Abdelkarim S
机构信息
Division of Radiation Medicine, Paul Scherrer Institute, Villigen, Switzerland.
出版信息
Nat Clin Pract Oncol. 2005 Sep;2(9):473-7; quiz 1 p following 477. doi: 10.1038/ncponc0294.
BACKGROUND
A 43-year-old Caucasian man presented with enlarged right laterocervical lymph nodes, and a 6-month history of diarrhea and 9 kg weight loss. His previous medical history was unremarkable. Physical examination and a cervical CT scan showed several indistinct necrotic right laterocervical lymph nodes of 4 cm maximal diameter, but with no lesions of the respiratory or digestive tracts.
INVESTIGATIONS
Physical examination, cervical CT scan, laterocervical lymph node biopsy, laboratory tests, and endoscopy.
DIAGNOSIS
Clinical stage 4 AIDS with stage T0 I1 S1 epidemic AIDS-related Kaposi's sarcoma of the laterocervical lymph nodes and, subsequently, the larynx.
MANAGEMENT
Highly active antiretroviral treatment (stavudine, didanosine, and nelfinavir), tracheotomy, and palliative radiotherapy.
背景
一名43岁的白人男性出现右侧颈外侧淋巴结肿大，有6个月腹泻病史且体重减轻9千克。他既往病史无异常。体格检查及颈部CT扫描显示右侧颈外侧有几个边界不清的坏死淋巴结，最大直径4厘米，但呼吸道和消化道无病变。
检查
体格检查、颈部CT扫描、颈外侧淋巴结活检、实验室检查及内镜检查。
诊断
临床4期艾滋病，伴有T0 I1 S1期流行型艾滋病相关的颈外侧淋巴结及随后喉部的卡波西肉瘤。
治疗
高效抗逆转录病毒治疗（司他夫定、去羟肌苷和奈非那韦）、气管切开术及姑息性放疗。
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