Dmochowski Jacek, Hoffmann Kenneth R, Singh Vikas, Xu Jinhui, Nazareth Daryl P
Department of Mathematics and Statistics, UNC Charlotte, 9201 University City Boulevard, Charlotte, North Carolina 28223-0001, USA.
Med Phys. 2005 Sep;32(9):2862-9. doi: 10.1118/1.2008467.
Two or more angiograms are being used frequently in medical imaging to reconstruct locations in three-dimensional (3D) space, e.g., for reconstruction of 3D vascular trees, implanted electrodes, or patient positioning. A number of techniques have been proposed for this task. In this simulation study, we investigate the effect of the shape of the configuration of the points in 3D (the "cloud" of points) on reconstruction errors for one of these techniques developed in our laboratory. Five types of configurations (a ball, an elongated ellipsoid (cigar), flattened ball (pancake), flattened cigar, and a flattened ball with a single distant point) are used in the evaluations. For each shape, 100 random configurations were generated, with point coordinates chosen from Gaussian distributions having a covariance matrix corresponding to the desired shape. The 3D data were projected into the image planes using a known imaging geometry. Gaussian distributed errors were introduced in the x and y coordinates of these projected points. Gaussian distributed errors were also introduced into the gantry information used to calculate the initial imaging geometry. The imaging geometries and 3D positions were iteratively refined using the enhanced-Metz-Fencil technique. The image data were also used to evaluate the feasible R-t solution volume. The 3D errors between the calculated and true positions were determined. The effects of the shape of the configuration, the number of points, the initial geometry error, and the input image error were evaluated. The results for the number of points, initial geometry error, and image error are in agreement with previously reported results, i.e., increasing the number of points and reducing initial geometry and/or image error, improves the accuracy of the reconstructed data. The shape of the 3D configuration of points also affects the error of reconstructed 3D configuration; specifically, errors decrease as the "volume" of the 3D configuration increases, as would be intuitively expected, and shapes with larger spread, such as spherical shapes, yield more accurate reconstructions. These results are in agreement with an analysis of the solution volume of feasible geometries and could be used to guide selection of points for reconstruction of 3D configurations from two views.
在医学成像中,经常使用两幅或更多幅血管造影图像来重建三维(3D)空间中的位置,例如用于重建三维血管树、植入电极或患者定位。针对此任务已经提出了许多技术。在本模拟研究中,我们研究了三维空间中配置点的形状(“点云”)对我们实验室开发的其中一种技术的重建误差的影响。评估中使用了五种类型的配置(一个球体、一个细长椭球体(雪茄形)、扁平球体(薄饼形)、扁平雪茄形以及带有单个远点的扁平球体)。对于每种形状,生成了100种随机配置,点坐标从具有与所需形状相对应的协方差矩阵的高斯分布中选取。使用已知的成像几何将三维数据投影到图像平面中。在这些投影点的x和y坐标中引入高斯分布误差。高斯分布误差也被引入到用于计算初始成像几何的机架信息中。使用增强型梅茨 - 芬西尔技术对成像几何和三维位置进行迭代优化。图像数据也用于评估可行的R - t解空间。确定计算位置与真实位置之间的三维误差。评估了配置形状、点数、初始几何误差和输入图像误差的影响。关于点数、初始几何误差和图像误差的结果与先前报道的结果一致,即增加点数以及减少初始几何和/或图像误差可提高重建数据的准确性。三维配置点的形状也会影响重建三维配置的误差;具体而言,可以直观地预期,随着三维配置的“体积”增加,误差会减小,并且具有更大分布范围的形状,如球形,会产生更准确的重建结果。这些结果与对可行几何解空间的分析一致,可用于指导从两个视图重建三维配置时的点选择。