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全胃切除术伴或不伴腹腔引流管。一项前瞻性随机试验。

Total gastrectomy with or without abdominal drains. A prospective randomized trial.

作者信息

Alvarez Uslar R, Molina H, Torres O, Cancino A

机构信息

Departamento de Cirugía, Universidad de Concepción, Chile.

出版信息

Rev Esp Enferm Dig. 2005 Aug;97(8):562-9. doi: 10.4321/s1130-01082005000800004.

Abstract

The most common postoperative complications of total gastrectomy are esophagojejunal anastomotic leakage and subphrenic abscess. These complications are a cause of morbidity and mortality, relaparotomy, and longer postoperative stay. The use of abdominal drains is useful for the early diagnosis and management of anastomotic leaks. The aim of this study was to analyze our experience with total gastrectomy for gastric cancer in patients with and without abdominal drains, and to evaluate the results regarding postoperative morbidity, postoperative hospital stay, postoperative days for oral intake, relaparotomy and mortality. This prospective and randomized study examines the results in 60 consecutive patients (43 males and 17 females) with gastric cancer who underwent total gastrectomy in the Regional Clinical Hospital of Concepción, Chile, between 2000 and 2003. Patients were divided into two groups: group I (without drains) and group II (two drains). We found 31 patients in group I and 29 patients in group II. The mean length of postoperative stay was 12.9 days in group I and 18.8 days in group II (p = 0.0242, s.). Morbidity was 9.7% in group I and 37.9% in group II (p = 0.0242, s.). Re-explorations were more frequent in group II (24.1%) versus group I (9.7%) (p = 0.1239, n.s.). Postoperative days for oral intake were 9.4 in group I and 12.8 in group II (p = 0.0514, n.s.) Mortality was 0% in group I and 3.4% in group II (p = 0.4833, n.s.). In our experience, morbidity and postoperative hospital stay were statistically higher in the group of patients with abdominal drains.

摘要

全胃切除术后最常见的并发症是食管空肠吻合口漏和膈下脓肿。这些并发症是导致发病和死亡、再次剖腹手术以及术后住院时间延长的原因。使用腹腔引流管有助于吻合口漏的早期诊断和处理。本研究的目的是分析我们在有或没有放置腹腔引流管的胃癌患者中进行全胃切除术的经验,并评估术后发病率、术后住院时间、术后开始经口进食的天数、再次剖腹手术及死亡率等结果。这项前瞻性随机研究对2000年至2003年期间在智利康塞普西翁地区临床医院接受全胃切除术的60例连续胃癌患者(43例男性和17例女性)的结果进行了研究。患者分为两组:第一组(未放置引流管)和第二组(放置两根引流管)。我们发现第一组有31例患者,第二组有29例患者。第一组术后平均住院时间为12.9天,第二组为18.8天(p = 0.0242,有统计学意义)。第一组的发病率为9.7%,第二组为37.9%(p = 0.0242,有统计学意义)。第二组(24.1%)的再次探查频率高于第一组(9.7%)(p = 0.1239,无统计学意义)。第一组术后开始经口进食的天数为9.4天,第二组为12.8天(p = 0.0514,无统计学意义)。第一组的死亡率为0%,第二组为3.4%(p = 0.4833,无统计学意义)。根据我们的经验,放置腹腔引流管的患者组在发病率和术后住院时间方面在统计学上更高。

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