Ioannidis Orestis, Anestiadou Elissavet, Koltsida Angeliki, Ramirez Jose M, Fabbri Nicolò, Ubieto Javier Martínez, Feo Carlo Vittorio, Pesce Antonio, Rosetzka Kristyna, Arroyo Antonio, Kocián Petr, Sánchez-Guillén Luis, Bellosta Ana Pascual, Whitley Adam, Enguita Alejandro Bona, Teresa-Fernandéz Marta, Bitsianis Stefanos, Symeonidis Savvas
Fourth Department of Surgery, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, General Hospital "George Papanikolaou", 57010 Thessaloniki, Greece.
Institute for Health Research Aragón, 50009 Zaragoza, Spain.
Diseases. 2025 Jul 22;13(8):231. doi: 10.3390/diseases13080231.
BACKGROUND/OBJECTIVES: Despite advancements in surgery, esophagectomy remains one of the most challenging and complex gastrointestinal surgical procedures, burdened by significant perioperative morbidity and mortality rates, as well as high financial costs. Recognizing the need for standardized care provided by a multidisciplinary healthcare team, the EUropean PErioperative MEdical Networking (EUPEMEN) initiative developed a dedicated protocol for perioperative care of patients undergoing esophagectomy, aiming to enhance recovery, reduce morbidity, and homogenize care delivery across European healthcare systems.
Developed through a multidisciplinary European collaboration of five partners, the protocol incorporates expert consensus and the latest scientific evidence. It addresses the entire perioperative pathway, from preoperative preparation to hospital discharge and postoperative recovery, emphasizing patient-centered care, risk mitigation, and early functional restoration.
The implementation of the EUPEMEN esophagectomy protocol is expected to improve patient outcomes through a day-by-day structured prehabilitation plan, meticulous intraoperative management, and proactive postoperative rehabilitation. The approach promotes reduced postoperative complications, earlier return to oral intake, and shorter hospital stays, while supporting multidisciplinary coordination.
The EUPEMEN protocol for esophagectomy provides a comprehensive guideline framework for optimizing perioperative care in esophageal surgery. In addition, it serves as a practical guide for healthcare professionals committed to advancing surgical recovery and standardizing clinical practice across diverse care environments across Europe.
背景/目的：尽管手术技术有所进步，但食管切除术仍然是最具挑战性和复杂性的胃肠道手术之一，围手术期发病率和死亡率较高，且费用高昂。认识到多学科医疗团队提供标准化护理的必要性，欧洲围手术期医学网络（EUPEMEN）倡议制定了一项针对接受食管切除术患者的围手术期护理专用方案，旨在促进康复、降低发病率，并使欧洲各医疗系统的护理服务同质化。
该方案由五个合作伙伴通过欧洲多学科合作制定，纳入了专家共识和最新科学证据。它涵盖了从术前准备到出院及术后康复的整个围手术期路径，强调以患者为中心的护理、风险降低和早期功能恢复。
预计EUPEMEN食管切除方案的实施将通过每日结构化的术前康复计划、细致的术中管理和积极的术后康复来改善患者预后。该方法有助于减少术后并发症、更早恢复经口进食并缩短住院时间，同时支持多学科协调。
EUPEMEN食管切除方案为优化食管手术的围手术期护理提供了一个全面的指南框架。此外，它还为致力于促进手术康复并在欧洲不同护理环境中规范临床实践的医疗专业人员提供了实用指南。
