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定时排尿对成人尿失禁管理的效果:系统评价

Effects of timed voiding for the management of urinary incontinence in adults: systematic review.

作者信息

Ostaszkiewicz Joan, Roe Brenda, Johnston Linda

机构信息

Co-ordinator Aged Care and Rehabilitation Nursing Research, Peter James Centre, School of Nursing, Deakin University, Burwood, Victoria, Australia.

出版信息

J Adv Nurs. 2005 Nov;52(4):420-31. doi: 10.1111/j.1365-2648.2005.03608.x.

Abstract

AIM

The aim of this paper is to present a systematic review assessing the effectiveness of timed voiding for the management of urinary incontinence in adults.

BACKGROUND

Despite the widespread use of systematic voiding programmes, their effectiveness is unclear, and the evidence for timed voiding has not been subject to rigorous and systematic evaluation. The impact on psychosocial factors and cost is also untested. The physiological basis for timed voiding is also poorly established.

METHODS

The systematic review incorporated the methodology of the Cochrane Collaboration. All randomized or quasi-randomized controlled trials that addressed timed voiding for the management of urinary incontinence in adults were searched, appraised, analysed and summarized. The date of the latest search was 2002. Data were extracted independently and appraised according to the level of concealment of random allocation prior to formal entry; few and identifiable withdrawals and dropouts and an analysis based on an intention to treat. The relative risk for dichotomous data was calculated with 95% confidence intervals. Where data were insufficient to support quantitative analysis, a narrative overview was undertaken.

RESULTS

Two trials of timed voiding met the inclusion criteria. In both, timed voiding was combined with other strategies. Participants were predominantly cognitively and physically impaired older women who resided in nursing home settings. Within-group improvements for the intervention groups were reported for both trials. One trial additionally reported a statistically significant reduction in night-time incontinence for the intervention group. The quality of the trials was modest and interpretation was limited by the potential for bias associated with inadequate concealment, missing data and no analysis by intention to treat.

CONCLUSION

Terms used to describe voiding programmes that involve a fixed interval of voiding are variable. No conclusions can be drawn at this point about the effectiveness of timed voiding for the management of urinary incontinence in adults.

摘要

目的

本文旨在进行一项系统评价,评估定时排尿对成人尿失禁管理的有效性。

背景

尽管系统排尿方案被广泛应用,但其有效性尚不清楚,且定时排尿的证据尚未经过严格和系统的评估。其对心理社会因素和成本的影响也未得到检验。定时排尿的生理基础也尚未明确确立。

方法

该系统评价采用了Cochrane协作网的方法。检索、评估、分析和总结了所有针对成人尿失禁管理中定时排尿的随机或半随机对照试验。最新检索日期为2002年。数据由独立提取,并根据正式纳入前随机分配的隐藏程度、少量且可识别的退出和失访情况以及基于意向性治疗的分析进行评估。二分类数据的相对风险采用95%置信区间计算。当数据不足以支持定量分析时,进行叙述性综述。

结果

两项定时排尿试验符合纳入标准。在这两项试验中,定时排尿均与其他策略相结合。参与者主要是居住在养老院的认知和身体有障碍的老年女性。两项试验均报告了干预组组内的改善情况。一项试验还报告干预组夜间尿失禁有统计学显著减少。试验质量一般,解释受到与隐藏不足、数据缺失以及未进行意向性治疗分析相关的潜在偏倚的限制。

结论

用于描述涉及固定排尿间隔的排尿方案的术语各不相同。目前无法就定时排尿对成人尿失禁管理的有效性得出结论。

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