Kadowaki Toru, Hamada Hironobu, Yokoyama Akihito, Katayama Hitoshi, Aramoto Takayoshi, Ueda Norifumi, Tomioka Hiromi, Higaki Jitsuo
Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
Respirology. 2005 Nov;10(5):689-91. doi: 10.1111/j.1440-1843.2005.00771.x.
An unusual thymic carcinoma in a 74-year-old woman is described. Initial chest CT revealed a mass at the mid-posterior mediastinum. Transbronchial fine needle biopsy of the mass failed to provide a definite diagnosis. The mass was treated as a malignant mediastinal tumour, and chemoradiotherapy was performed as initial treatment. The patient died 5 years after receiving primary treatment. The results of postmortem microscopic examination, including immunohistochemical study with CD5 antibody, were consistent with thymic carcinoma. This case is interesting in that the mid-posterior mediastinum is the site where thymic carcinoma is least likely to originate.
本文描述了一名74岁女性患有的罕见胸腺癌。最初的胸部CT显示中后纵隔有一个肿块。对该肿块进行经支气管细针穿刺活检未能得出明确诊断。该肿块被当作恶性纵隔肿瘤治疗,初始治疗采用了放化疗。患者在接受初次治疗5年后死亡。尸检显微镜检查结果,包括用CD5抗体进行的免疫组化研究,与胸腺癌相符。该病例的有趣之处在于中后纵隔是胸腺癌最不可能起源的部位。