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甲型流感季节性暴发的儿科特征及其在儿科急诊室和儿科病房的负担

[Pediatric features of an influenza A seasonal outbreak and its burden in pediatric emergency rooms and pediatric departments].

作者信息

Blanc P, Noël G, Dubus J C, Garnier J M, Chabrol B, Minodier P

机构信息

Urgences pédiatriques, CHU Nord, chemin des Bourrelly, 13915 Marseille cedex 20, France.

出版信息

Arch Pediatr. 2006 Jan;13(1):11-6. doi: 10.1016/j.arcped.2005.09.028. Epub 2005 Nov 3.

Abstract

AIM OF THE STUDY

To describe epidemiological features of an outbreak of flu A in hospitalized children and to evaluate the flu's burden in pediatric and pediatric emergencies departments.

POPULATION AND METHODS

Multicenter prospective study in 2 pediatric university hospitals, in Marseille, France. Nasal swabs for flu A were performed in all the febrile children admitted during winter 2003-2004. Pre and postoutbreak admissions in pediatric and pediatric emergencies departments were compared too.

RESULTS

During the outbreak, 941 children were admitted and 605 were tested for flu A. Nasal swabs were positive in 111. Attack's rate was 11.8%. In these children, infants under 2 years were 66%. Respiratory forms were uncommon, although febrile seizures and digestive troubles were much frequent. The mean hospitalization duration was almost 4 days. Flu A outbreak finally increased the pediatric and pediatric emergencies departments rates of admission, of 48% and 37% respectively.

CONCLUSION

Flu is frequently underestimated in children, especially in infants. Clinical forms are various. Child's vaccination is questionable in France.

摘要

研究目的

描述住院儿童甲型流感暴发的流行病学特征,并评估流感在儿科及儿科急诊科造成的负担。

研究对象与方法

在法国马赛的两家儿科大学医院进行多中心前瞻性研究。对2003 - 2004年冬季收治的所有发热儿童进行甲型流感鼻拭子检测。同时比较了儿科及儿科急诊科暴发前后的入院情况。

结果

暴发期间,共收治941名儿童,其中605名接受了甲型流感检测。111名鼻拭子检测呈阳性。感染率为11.8%。在这些儿童中,2岁以下婴儿占66%。呼吸道症状不常见,而热性惊厥和消化系统问题较为频繁。平均住院时间约为4天。甲型流感暴发最终使儿科及儿科急诊科的入院率分别提高了48%和37%。

结论

在儿童中,尤其是婴儿中,流感常常被低估。临床症状多样。在法国,儿童接种流感疫苗存在争议。

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