Emura T, Fujimoto S, Takahashi K P, Morisawa S, Inoue A
Department of Biochemistry, Osaka City University Medical School, Japan.
Biochem Int. 1992 Mar;26(3):531-5.
Nuclear S1 proteins are a group of proteins apparently ubiquitous in vertebrate cell nuclei. They were originally isolated at pH 4.9 from the supernatant of rat liver nuclei mildly digested with DNase I. In the present study, under the conditions identical to those employed for vertebrate cells, we identified two S1 proteins in the starfish Asterina Pectinifera. Their molecular weights are 47,200 and 39,000. This finding suggests widespread occurrence of S1 proteins in eukaryotes and their basic function in the cell nucleus.
核S1蛋白是一组在脊椎动物细胞核中明显普遍存在的蛋白质。它们最初是在pH 4.9的条件下，从用DNA酶I轻度消化的大鼠肝细胞核上清液中分离出来的。在本研究中，在与用于脊椎动物细胞相同的条件下，我们在海星栉孔扇贝中鉴定出了两种S1蛋白。它们的分子量分别为47,200和39,000。这一发现表明S1蛋白在真核生物中广泛存在及其在细胞核中的基本功能。
