Ke Hung-Yen, Chen Jia-Hui, Jen Yee-Min, Yu Jyh-Cherng, Hsieh Chung-Bao, Chen Cheng-Jueng, Liu Yao-Chi, Chen Teng-Wei, Chan De-Chuan
Division of General Surgery, Tri-Service General Hospital, 325, Sec. 2, Chen-Kung Road, Neihu 114, Taipei, Taiwan, China.
World J Gastroenterol. 2005 Oct 21;11(39):6235-7. doi: 10.3748/wjg.v11.i39.6235.
Hepatoblastoma is the most common primary hepatic tumor of children. However, only a very few cases have been reported in adults. Most studies support treatment with chemotherapy followed by surgical resection. We present the first reported case of adult hepatoblastoma in Taiwan. A 52-year-old female suffered from sudden onset of abdominal pain and general weakness for days. Internal bleeding with hemorrhagic shock was suspected and two massive lesions in both lobes of the liver with hemoperitoneum were noted from imaging studies. Surgical resection of the larger left lobe tumor and radio-frequency ablation of the right smaller one were performed. The histopathology diagnosis was of a hepatoblastoma.
肝母细胞瘤是儿童最常见的原发性肝脏肿瘤。然而,成人病例仅有极少数报道。大多数研究支持先进行化疗再行手术切除的治疗方法。我们报告台湾首例成人肝母细胞瘤病例。一名52岁女性数天来突发腹痛和全身乏力。怀疑有内出血并伴有失血性休克,影像学检查发现肝脏两叶有两个巨大病灶并伴有腹腔积血。对较大的左叶肿瘤进行了手术切除,对较小的右叶肿瘤进行了射频消融。组织病理学诊断为肝母细胞瘤。