Miyauchi K, Koyama H, Noguchi S, Inaji H, Yamamoto H, Kodama K, Iwanaga T
Department of Surgery, Kinki Central Hospital, Hyogo, Japan.
Eur J Cancer. 1992;28A(6-7):1059-62. doi: 10.1016/0959-8049(92)90456-c.
From 1977 to 1987, 23 patients with isolated chest wall recurrence, excluding sternal metastasis, from breast cancer underwent full thickness chest wall resection. The 5-year survival rate after chest wall resection was 48% but the 5-year relapse-free survival rate was 26%. Mediastinal metastasis was proved histologically at the time of chest wall resection in 7 patients, and survival period with mediastinal involvement was significantly (P less than 0.01) shorter than that with no mediastinal involvement (n = 16). In 17 patients with a long disease-free interval (DFI greater than or equal to 24 months), survival was longer than in 6 patients with a short DFI (less than 24 months). For the selected patients without mediastinal involvement and long DFI, surgical treatment for chest wall recurrence of breast cancer should play a significant role in improving the quality of life, and even in prolonging the survival rate.
1977年至1987年，23例乳腺癌孤立性胸壁复发（不包括胸骨转移）患者接受了胸壁全层切除术。胸壁切除术后的5年生存率为48%，但5年无复发生存率为26%。7例患者在胸壁切除时经组织学证实有纵隔转移，有纵隔受累的生存期明显（P＜0.01）短于无纵隔受累者（n = 16）。17例无病间期长（DFI≥24个月）的患者生存期长于6例无病间期短（＜24个月）的患者。对于所选的无纵隔受累且无病间期长的患者，乳腺癌胸壁复发的手术治疗在改善生活质量甚至延长生存率方面应发挥重要作用。
