Rosen P P, Groshen S, Kinne D W
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
J Natl Cancer Inst Monogr. 1992(11):159-62.
Seven hundred sixty-seven patients treated at the Memorial Sloan-Kettering Cancer Center from 1964 through 1970 by mastectomy and axillary dissection have now been followed for a median of 18 years. This unusual database consists of a consecutive series of women cared for by physicians specialized in the treatment of breast cancer in one institution. The data suggest that patients with T1, N0, M0 tumors of 1 cm or less may be "cured" by mastectomy and axillary dissection, the estimated proportion of "cured" patients being 89%. The data also suggest that node-negative patients can be placed in categories of risk for recurrence on the basis of primary tumor size.
1964年至1970年间在纪念斯隆-凯特琳癌症中心接受乳房切除术和腋窝淋巴结清扫术治疗的767名患者，目前已随访了18年，中位数为18年。这个独特的数据库包含了在一个机构中由专门治疗乳腺癌的医生连续护理的一系列女性患者。数据表明，肿瘤大小为1厘米或更小的T1、N0、M0期患者，通过乳房切除术和腋窝淋巴结清扫术可能会“治愈”，“治愈”患者的估计比例为89%。数据还表明，可根据原发肿瘤大小将淋巴结阴性患者分为复发风险类别。
