Margolese R
Department of Surgery, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
J Natl Cancer Inst Monogr. 1992(11):41-8.
Clinical trials have demonstrated that patients treated with lumpectomy and radiation therapy have long-term survival rates equivalent to those treated with classical forms of mastectomy. Perhaps questions remain about appropriate treatment of the very smallest and the largest of operable breast tumors, but the majority of patients with primary breast cancer can be successfully treated with conservative surgery and radiation. Factors involved in surgical decision making, technical features of lumpectomy, and postoperative treatment are discussed.
临床试验表明，接受肿块切除术和放射治疗的患者的长期生存率与接受传统乳房切除术的患者相当。对于最小和最大的可手术乳腺肿瘤的适当治疗可能仍存在疑问，但大多数原发性乳腺癌患者可以通过保守手术和放射治疗成功治愈。本文讨论了手术决策中涉及的因素、肿块切除术的技术特点以及术后治疗。
