van Maele-Fabry G, Delhaise F, Picard J J
Laboratory of Developmental Genetics, Université Catholique de Louvain, Belgium.
Int J Dev Biol. 1992 Mar;36(1):161-7.
A precise framework of morphological developmental events observed macroscopically in early postimplantation mouse embryos aged 8-10 days (0-30 somites) is established. The quantitative evolution of the developmental score of 16 features as a function of the developmental stage of the embryos (expressed in number of somites) is presented. Thirty-one groups of ten embryos, each with 0 to 30 somites, were scored for each feature according to the previous description of the authors. In addition, the variation of individual structures as a function of embryonic developmental stages is evaluated. It is suggested that the framework of differentiating individual structures at given developmental stages will help to plan experiments in developmental biology of rodents and will facilitate the interpretation of results in developmental toxicity.
建立了一个精确的形态发育事件框架，该框架是通过宏观观察8至10天大（0至30体节）的植入后早期小鼠胚胎得到的。呈现了16个特征的发育评分随胚胎发育阶段（以体节数量表示）的定量演变。根据作者之前的描述，对31组每组10个胚胎（每个胚胎有0至30个体节）的每个特征进行评分。此外，还评估了个体结构随胚胎发育阶段的变化。研究表明，给定发育阶段个体结构分化的框架将有助于规划啮齿动物发育生物学实验，并有助于解释发育毒性研究结果。
