Rowland Thomas, Moriarty Kevin, Banever Gregory
Division of Pediatric Cardiology, Department of Pediatrics, Baystate Medical Center Children's Hospital, Springfield, MA 01199, USA.
Arch Pediatr Adolesc Med. 2005 Nov;159(11):1069-73. doi: 10.1001/archpedi.159.11.1069.
To determine the magnitude of the effects of pectus excavatum deformity on endurance fitness and cardiorespiratory functional reserve in adolescent boys.
Cross-sectional comparison of cardiac and ventilatory variables at rest and during a maximal cycle exercise test.
Pediatric exercise-testing laboratory.
Twelve boys (mean +/- SD age, 14.1 +/- 1.8 years; age range, 11.8-18.0 years) with moderate-to-severe pectus excavatum deformity (mean +/- SD Haller index, 3.95 +/- 0.88) and 20 control boys (mean +/- SD age, 12.5 +/- 0.4 years; age range, 12.1-13.5 years) without musculoskeletal deformity.
Endurance fitness (physical work capacity); respiratory rate, tidal volume, and minute ventilation; and cardiac output and stroke volume by Doppler echocardiography.
Patients with pectus deformity had significantly lower endurance fitness than controls (mean +/- SD physical work capacity, 2.60 +/- 0.28 W . kg(-1) vs 3.11 +/- 0.45 W . kg(-1)) and reduced mean +/- SD values for maximal cardiac index (10.6 +/- 1.6 L . min(-1) vs 12.0 +/- 2.2 L . min(-1)) and peak tidal volume (3.02 +/- 0.27 mL . kg(-1) . 10(-2) vs 3.46 +/- 0.30 mL . kg(-1) . 10(-2)). However, considerable overlap was observed in these values between the 2 groups.
As a group, boys with pectus excavatum deformity have lower endurance fitness than controls, and this is associated with reduced cardiac output and tidal volume responses to exercise. However, the wide variability of these measures makes it difficult to assign pectus deformity as a cause of exercise intolerance in individual patients.
确定漏斗胸畸形对青春期男孩耐力适应性和心肺功能储备的影响程度。
在静息状态和最大强度循环运动试验期间，对心脏和通气变量进行横断面比较。
儿科运动测试实验室。
12名患有中度至重度漏斗胸畸形（平均±标准差哈勒指数，3.95±0.88）的男孩（平均±标准差年龄，14.1±1.8岁；年龄范围，11.8 - 18.0岁）和20名无肌肉骨骼畸形的对照男孩（平均±标准差年龄，12.5±0.4岁；年龄范围，12.1 - 13.5岁）。
耐力适应性（体力工作能力）；呼吸频率、潮气量和每分通气量；以及通过多普勒超声心动图测量的心输出量和每搏输出量。
漏斗胸畸形患者的耐力适应性显著低于对照组（平均±标准差体力工作能力，2.60±0.28 W·kg⁻¹ 对 3.11±0.45 W·kg⁻¹），最大心脏指数（10.6±1.6 L·min⁻¹ 对 12.0±2.2 L·min⁻¹）和峰值潮气量（3.02±0.27 mL·kg⁻¹·10⁻² 对 3.46±0.30 mL·kg⁻¹·10⁻²）的平均±标准差数值也降低。然而，两组之间在这些数值上存在相当大的重叠。
总体而言，患有漏斗胸畸形的男孩耐力适应性低于对照组，这与运动时心输出量和潮气量反应降低有关。然而，这些指标的广泛变异性使得难以将漏斗胸畸形确定为个体患者运动不耐受的原因。
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