Semelka R C, Shoenut J P, Greenberg H M, Bow E J
Department of Radiology, St Boniface General Hospital MRI Faculty, Winnipeg, Manitoba, Canada.
J Magn Reson Imaging. 1992 May-Jun;2(3):341-5. doi: 10.1002/jmri.1880020315.
Dynamic contrast-enhanced computed tomography (CT) was compared with 1.5-T magnetic resonance (MR) imaging with FLASH (fast low-angle shot), gadolinium-enhanced FLASH (Gd-FLASH), and T2-weighted fat-suppression (T2FS) sequences in 11 patients with hematologic malignancies, five with biopsy-confirmed hepatosplenic candidiasis treated with antifungal chemotherapy and six with a clinical history suggestive of acute hepatosplenic candidiasis. CT and MR images were separately interpreted in a prospective fashion. MR imaging showed lesions compatible with candidiasis in the liver in six patients, the spleen in five, and the kidneys in one. CT showed candidiasis-compatible lesions in the liver in three patients and the spleen in one; no renal lesions were shown. Differences between acute and treated candidal lesions were observed. Gd-FLASH images showed the most liver lesions (n = 106), followed by FLASH (n = 85), T2FS (n = 20), and CT (n = 18). MR imaging performed better than CT in distinguishing candidal hepatic lesions from recurrent lymphoblastic lymphoma in one patient and from hepatic infarcts in another. The results suggest that MR imaging may be superior to CT in detecting lesions of hepatosplenic candidiasis.
对11例血液系统恶性肿瘤患者进行了动态对比增强计算机断层扫描（CT）与1.5-T磁共振（MR）成像比较，其中5例经活检证实为肝脾念珠菌病且接受抗真菌化疗，6例有提示急性肝脾念珠菌病的临床病史。CT和MR图像以前瞻性方式分别解读。MR成像显示6例患者肝脏、5例患者脾脏及1例患者肾脏有符合念珠菌病的病变。CT显示3例患者肝脏及1例患者脾脏有符合念珠菌病的病变；未显示肾脏病变。观察到急性念珠菌病变与已治疗念珠菌病变之间的差异。钆增强快速低角度激发（Gd-FLASH）图像显示的肝脏病变最多（n = 106），其次是快速低角度激发（FLASH）（n = 85）、T2加权脂肪抑制（T2FS）（n = 20）和CT（n = 18）。在1例患者中，MR成像在区分念珠菌性肝病变与复发性淋巴细胞性淋巴瘤以及在另1例患者中区分与肝梗死方面比CT表现更好。结果表明，MR成像在检测肝脾念珠菌病病变方面可能优于CT。
