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[儿童及青少年银屑病的治疗选择]

[Therapy options for psoriasis in childhood and adolescence].

作者信息

Zappel Kristina, Sterry Wolfram, Blume-Peytavi Ulrike

机构信息

Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Charité Campus Mitte.

出版信息

J Dtsch Dermatol Ges. 2004 May;2(5):329-42. doi: 10.1046/j.1439-0353.2004.04061.x.

Abstract

Up to 30% of all psoriatic patients show their first symptoms during childhood and adolescence. In 1/4 of these children, psoriatic lesions appear within the first two years of life. The treatment of pediatric psoriasis differs considerably in several ways from that of adults. Not only the age and intensity but also physical development, prognostic criteria and social background should be considered. Standard procedures, clinical trials of high quality and therapeutic guidelines for psoriasis in childhood are still lacking. This review surveys the therapeutic management of pediatric and juvenile psoriasis. Current topical and systemic therapy options are critically reviewed. Prevention as well as enhancement of quality of life are also considered.

摘要

高达30%的银屑病患者在儿童期和青少年期出现首发症状。在这些儿童中,四分之一的患者在生命的头两年内出现银屑病皮损。儿童银屑病的治疗在几个方面与成人有很大不同。不仅要考虑年龄和强度,还要考虑身体发育、预后标准和社会背景。目前仍缺乏针对儿童银屑病的标准程序、高质量临床试验和治疗指南。本文综述了儿童和青少年银屑病的治疗管理。对当前的局部和全身治疗方案进行了批判性评价,并考虑了预防以及生活质量的提高。

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