Yonemitsu Koichiro, Sugihara Shigenori, Toyama Eiichiro, Tsuruta Yutaka, Teshima Kenichi, Tanaka Mutsuo
Dept. of Gastroenterological Surgery, Shimonoseki Welfare Social Hospital.
Gan To Kagaku Ryoho. 2005 Nov;32(12):1963-6.
We followed patients who underwent hepatic arterial infusion chemotherapy with low-dose CDDP+5-FU for liver metastases from colorectal cancer in the outpatient setting. A catheter was inserted from the femoral artery into the proper hepatic artery using the interventional technique. Two complete response (CR) and seven partial response (PR) were achieved, but later 2 of these patients had lung metastases. We conclude that this therapy may be effective, but control of extrahepatic lesions is necessary for life prolongation.
我们在门诊环境中对接受低剂量顺铂+5-氟尿嘧啶肝动脉灌注化疗的结直肠癌肝转移患者进行了随访。采用介入技术经股动脉将导管插入肝固有动脉。获得了2例完全缓解（CR）和7例部分缓解（PR），但后来这些患者中有2例发生了肺转移。我们得出结论，这种治疗可能有效，但为了延长生命，控制肝外病变是必要的。
