Golubeva M G, Grigoreva M E, Smirnova M P
Department of Human and Animals Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow.
Bull Exp Biol Med. 2005 Aug;140(2):162-4. doi: 10.1007/s10517-005-0434-8.
We studied the effect of vasopressin analogue desglycinamide-arginine-vasopressin on changes in platelet hemostasis produced by intragastric administration of Ticlid or clopidogrel (inhibitors of ADP-induced platelet aggregation). Intranasal administration of the peptide under conditions of hemorrhagic diathesis produced a hemostatic effect and normalized some parameters of blood coagulation.
我们研究了血管加压素类似物去甘氨酰胺 - 精氨酸 - 血管加压素对经胃内给予噻氯匹定或氯吡格雷（ADP诱导的血小板聚集抑制剂）所产生的血小板止血变化的影响。在出血素质的情况下经鼻给予该肽产生了止血作用，并使一些血液凝固参数恢复正常。
