Downie I, Gardiner D S, Downie T T, Gibson I W, Kenyon C, More I A, Lindop G B
Department of Pathology, University of Glasgow, UK.
Cell Tissue Res. 1992 Jun;268(3):567-70. doi: 10.1007/BF00319164.
The peripolar cell is a unique cell type in the mammalian glomerulus. Peripolar cells are said to be identifiable during light microscopy by their cytoplasmic granules and by their position at the vascular pole; and during scanning electron microscopy by their distinctive surface morphology. We used both techniques to count peripolar cells in 6 normal rat kidneys. Scanning microscopy revealed that 55(+/- 5)% of glomeruli contained at least one peripolar cell whereas light microscopy revealed granulated peripolar cells in only 4(+/- 2)% of glomeruli. Vascular poles which contained peripolar cells previously identified by scanning were then examined by light and by transmission electron microscopy. Serial sections through these peripolar cells demonstrated the absence of cytoplasmic granules. Our observations suggest that the majority of peripolar cells in the rat contain no granules.
极周细胞是哺乳动物肾小球中一种独特的细胞类型。据说，在光学显微镜下，极周细胞可通过其细胞质颗粒及其在血管极的位置来识别；在扫描电子显微镜下，则可通过其独特的表面形态来识别。我们使用这两种技术对6只正常大鼠肾脏中的极周细胞进行计数。扫描显微镜显示，55（±5）%的肾小球至少含有一个极周细胞，而光学显微镜仅在4（±2）%的肾小球中发现有颗粒状极周细胞。然后，对先前通过扫描鉴定出含有极周细胞的血管极进行光学显微镜和透射电子显微镜检查。通过这些极周细胞的连续切片显示没有细胞质颗粒。我们的观察结果表明，大鼠中的大多数极周细胞不含颗粒。
