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肾小球极周细胞:综述

The glomerular peripolar cell: a review.

作者信息

Gardiner D S, Downie I, Gibson I W, More I A, Lindop G B

机构信息

University of Glasgow, Pathology Department, Western Infirmary, United Kingdom.

出版信息

Histol Histopathol. 1991 Oct;6(4):567-73.

PMID:1804435
Abstract

There is now morphological evidence from several species that the peripolar cell is a distinctive glomerular cell which may have a secretory function, although a secretory product has not been identified. Peripolar cells, like other glomerular epithelial cells, probably absorb plasma proteins from the glomerular filtrate. Peripolar cells may participate in regulation of sodium balance and the changes in renal function which occur at the time of birth. They are ideally situated to monitor the composition of the glomerular filtrate and/or the calibre of the glomerular arterioles. The relationship between peripolar cells and other granulated glomerular epithelial cells must be clarified, however their morphology and unique anatomical site is suggestive of a specialised function.

摘要

现在有来自几个物种的形态学证据表明,极周细胞是一种独特的肾小球细胞,可能具有分泌功能,尽管尚未鉴定出分泌产物。极周细胞与其他肾小球上皮细胞一样,可能从肾小球滤液中吸收血浆蛋白。极周细胞可能参与钠平衡的调节以及出生时发生的肾功能变化。它们所处的位置非常适合监测肾小球滤液的成分和/或肾小球小动脉的管径。然而,必须阐明极周细胞与其他颗粒状肾小球上皮细胞之间的关系,不过它们的形态和独特的解剖位置表明其具有特殊功能。

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