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心力衰竭的非移植手术替代方案。

Nontransplant surgical alternatives for heart failure.

作者信息

McGee Edwin C, Grady Kathleen L, McCarthy Patrick M

机构信息

Bluhm Cardiovascular Institute, Northwestern University's Feinberg School of Medicine, Division of Cardiothoracic Surgery, Galter 10-105, 201 East Huron Street, Chicago, IL 60611-2908, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2005 Dec;7(6):491-501. doi: 10.1007/s11936-005-0035-x.

Abstract

Heart failure is a tremendous burden on society, and on the health care system in particular. Historically, medical treatments have been the only therapies available because patients were felt to be too high risk to undergo conventional cardiac surgical procedures. Cardiac transplantation remains an established therapy for certain patients with end-stage heart failure but it is limited by donor availability and the need for lifelong immunosuppression. Recent advances in myocardial protection, operative techniques, and perioperative care have made it possible for conventional surgery, such as coronary bypass, ventricular reconstruction, and valve repair, to be offered to many patients with advanced heart failure with good short- and long-term results. In 2005, few patients are inoperable.

摘要

心力衰竭给社会带来了巨大负担,尤其是给医疗保健系统带来了沉重压力。从历史上看,医疗治疗一直是唯一可用的疗法,因为人们认为患者接受传统心脏外科手术的风险过高。心脏移植仍然是某些终末期心力衰竭患者的既定治疗方法,但它受到供体可用性和终身免疫抑制需求的限制。心肌保护、手术技术和围手术期护理方面的最新进展使得传统手术,如冠状动脉搭桥术、心室重建术和瓣膜修复术,能够提供给许多晚期心力衰竭患者,并取得了良好的短期和长期效果。在2005年,几乎没有患者无法进行手术。

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