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Decreased risk of acute gastrointestinal toxicity when substituting methotrexate with mycophenolate mofetil in the prevention of graft-versus-host disease in stem cell transplantation following myeloablative conditioning regimens.

作者信息

Pohlreich D, Vitek A, Maalouf J, Cetkovsky P

出版信息

Bone Marrow Transplant. 2006 Jan;37(2):235-6; author reply 236-7. doi: 10.1038/sj.bmt.1705227.

DOI:10.1038/sj.bmt.1705227
PMID:16284607
Abstract
摘要

相似文献

1
Decreased risk of acute gastrointestinal toxicity when substituting methotrexate with mycophenolate mofetil in the prevention of graft-versus-host disease in stem cell transplantation following myeloablative conditioning regimens.在清髓性预处理方案后的干细胞移植中，用霉酚酸酯替代甲氨蝶呤预防移植物抗宿主病时，急性胃肠道毒性风险降低。
Bone Marrow Transplant. 2006 Jan;37(2):235-6; author reply 236-7. doi: 10.1038/sj.bmt.1705227.
2
Tailoring the GVHD prophylaxis regimen according to transplantation associated toxicities-Substituting the 3rd dose of methotrexate to mycophenolate mofetil.根据移植相关毒性调整移植物抗宿主病预防方案-用吗替麦考酚酯替代甲氨蝶呤第 3 剂。
Leuk Res. 2014 Aug;38(8):913-7. doi: 10.1016/j.leukres.2014.05.020. Epub 2014 Jun 4.
3
A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation.一项前瞻性随机试验，比较环孢素与短疗程甲氨蝶呤联合环孢素和霉酚酸酯在清髓性异基因骨髓移植中预防移植物抗宿主病的效果。
Bone Marrow Transplant. 2004 Oct;34(7):621-5. doi: 10.1038/sj.bmt.1704647.
4
A phase I/II study of mycophenolate mofetil in combination with cyclosporine for prophylaxis of acute graft-versus-host disease after myeloablative conditioning and allogeneic hematopoietic cell transplantation.霉酚酸酯联合环孢素预防清髓性预处理和异基因造血细胞移植后急性移植物抗宿主病的I/II期研究。
Biol Blood Marrow Transplant. 2005 Jul;11(7):495-505. doi: 10.1016/j.bbmt.2005.03.006.
5
Cyclosporine A and mycophenolate mofetil vs cyclosporine A and methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings.环孢素A与霉酚酸酯对比环孢素A与甲氨蝶呤用于预防来自 HLA 同型同胞的干细胞移植后的移植物抗宿主病
Bone Marrow Transplant. 2005 Jun;35(11):1089-93. doi: 10.1038/sj.bmt.1704956.
6
Unrelated donor granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cell transplantation after nonmyeloablative conditioning: the effect of postgrafting mycophenolate mofetil dosing.非清髓性预处理后无关供者粒细胞集落刺激因子动员的外周血单个核细胞移植：移植后霉酚酸酯给药剂量的影响
Biol Blood Marrow Transplant. 2006 Apr;12(4):454-65. doi: 10.1016/j.bbmt.2005.12.030.
7
Long-term follow-up of a prospective randomized trial comparing CYA and MTX with CYA and mycophenolate mofetil for GVHD prophylaxis in myeloablative sibling donor hematopoietic cell transplantation.一项前瞻性随机试验的长期随访，该试验比较了环孢素A（CYA）联合甲氨蝶呤（MTX）与CYA联合霉酚酸酯用于清髓性同胞供者造血细胞移植中预防移植物抗宿主病（GVHD）的效果。
Bone Marrow Transplant. 2013 Nov;48(12):1578-80. doi: 10.1038/bmt.2013.89. Epub 2013 Jun 10.
8
Degree of mucositis and duration of neutropenia are the major risk factors for early post-transplant febrile neutropenia and severe bacterial infections after reduced-intensity conditioning.黏膜炎的严重程度和中性粒细胞减少的持续时间是导致低强度预处理后移植后早期发热性中性粒细胞减少和严重细菌感染的主要危险因素。
Eur J Haematol. 2012 Jan;88(1):46-51. doi: 10.1111/j.1600-0609.2011.01724.x.
9
Response to mycophenolate mofetil therapy in refractory chronic graft-versus-host disease.霉酚酸酯治疗难治性慢性移植物抗宿主病的疗效
Haematologica. 2003 Jul;88(7):837-9.
10
Reduced-intensity conditioning allogeneic transplantation from unrelated donors: evaluation of mycophenolate mofetil plus cyclosporin A as graft-versus-host disease prophylaxis.来自无关供者的减低强度预处理异基因移植：霉酚酸酯联合环孢素A预防移植物抗宿主病的评估
Biol Blood Marrow Transplant. 2008 Jun;14(6):664-71. doi: 10.1016/j.bbmt.2008.03.007.

引用本文的文献

1
Inferior Outcomes with Cyclosporine and Mycophenolate Mofetil after Myeloablative Allogeneic Hematopoietic Cell Transplantation.在清髓性异基因造血细胞移植后，环孢素和霉酚酸酯的预后较差。
Biol Blood Marrow Transplant. 2019 Sep;25(9):1744-1755. doi: 10.1016/j.bbmt.2019.05.019. Epub 2019 May 31.
2
Comparison of cyclosporine and tacrolimus combined with mycophenolate mofetil in prophylaxis for graft-versus-host disease after reduced-intensity umbilical cord blood transplantation.环孢素与他克莫司联合霉酚酸酯用于降低强度脐带血移植后移植物抗宿主病预防的比较
Int J Hematol. 2017 Jan;105(1):92-99. doi: 10.1007/s12185-016-2093-0. Epub 2016 Sep 29.