Emeribe A O, Igweagu C A, Osim E E
Department of Haematology, University of Calabar, Nigeria.
East Afr Med J. 1992 Jan;69(1):27-30.
One hundred and seventy six healthy residents of Calabar Municipality were investigated for the presence of salivary ABH substances. Saliva and blood samples collected were analysed by haemagglutination inhibition and standard tube ABO grouping methods respectively. 86.90% and 13.10% of the subjects were ABH secretors and non-secretors respectively. A significant correlation was established between the secretor status frequency and ABO blood group phenotypes (P less than 0.001). No correlation was established with age or sex. O blood group subjects had higher titre of H-substances than A and B subjects while AB subjects had the lowest. In AB subjects, the A titre was usually higher than that of B substances. The gene frequencies for Se and se were 0.6390 and 0.3610 respectively while the phenotype prevalence rates for Se/se, Se se and se se were 40.83%, 46.15% and 13.10% respectively. It is concluded that the prevalence rate of non-secretors which has been associated with the occurrence of duodenal ulcer is low in the locality.
对卡拉巴尔市176名健康居民进行了唾液ABH物质检测。分别采用血凝抑制法和标准试管ABO血型分组法对采集的唾液和血液样本进行分析。研究对象中,ABH分泌者和非分泌者分别占86.90%和13.10%。分泌者状态频率与ABO血型表型之间存在显著相关性(P<0.001)。与年龄或性别无相关性。O型血受试者的H物质滴度高于A型和B型受试者,而AB型受试者的H物质滴度最低。在AB型受试者中,A物质的滴度通常高于B物质。Se和se的基因频率分别为0.6390和0.3610,而Se/se、Se se和se se的表型流行率分别为40.83%、46.15%和13.10%。研究得出结论,在该地区,与十二指肠溃疡发生相关的非分泌者流行率较低。