Abramowicz Weronika N, Galloway Stuart D R
Dept of Sports Studies, University of Stirling, Stirling, Scotland.
Int J Sport Nutr Exerc Metab. 2005 Aug;15(4):386-400. doi: 10.1123/ijsnem.15.4.386.
Twelve healthy active subjects (6 male, 6 female) performed 60 min of exercise (60% VO(2max)) on 3 occasions after supplementing with L-Carnitine L-tartrate (LCLT) or placebo. Each subject received a chronic dose, an acute dose, and placebo in a randomized, double-blind crossover design. Dietary intake and exercise were replicated for 2 d prior to each trial. In males there was a significant difference in rate of carbohydrate (CHO) oxidation between placebo and chronic trials (P = 0.02) but not placebo and acute trials (P = 0.70), and total CHO oxidation was greater following chronic supplementation vs. placebo )mean +/- standard deviation) of 93.8 (17.3) g/hr and 78.2 (23.3) g/h, respectively). In females, no difference in rate of, or total, CHO oxidation was observed between trials. No effects on fat oxidation or hematological responses were noted in either gender group. Under these experimental conditions, chronic LCLT supplementation increased CHO oxidation in males during exercise but this was not observed in females.
12名健康的活跃受试者（6名男性，6名女性）在补充左旋肉碱酒石酸盐（LCLT）或安慰剂后，分3次进行了60分钟的运动（60%最大摄氧量）。每位受试者在随机、双盲交叉设计中接受了慢性剂量、急性剂量和安慰剂。在每次试验前，饮食摄入和运动重复2天。在男性中，安慰剂组和慢性试验组之间的碳水化合物（CHO）氧化速率存在显著差异（P = 0.02），但安慰剂组和急性试验组之间无显著差异（P = 0.70），慢性补充后总CHO氧化量高于安慰剂组（平均值±标准差），分别为93.8（17.3）克/小时和78.2（23.3）克/小时）。在女性中，各试验组之间未观察到CHO氧化速率或总量的差异。在任何一个性别组中，均未观察到对脂肪氧化或血液学反应的影响。在这些实验条件下，慢性补充LCLT可增加男性运动期间的CHO氧化，但在女性中未观察到这种现象。
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