Applied Science & Performance Institute, Research Division, Tampa, FL 33607, USA.
Lonza Consumer Health Inc., Morristown, NJ 07960, USA.
Nutrients. 2021 Sep 28;13(10):3432. doi: 10.3390/nu13103432.
L-carnitine tartrate has been shown to improve relatively short-term recovery among athletes. However, there is a lack of research on the longer-term effects in the general population.
The primary objectives of this randomized double-blind, placebo-controlled trial were to evaluate the effects of daily L-carnitine tartrate supplementation for 5 weeks on recovery and fatigue.
In this study, eighty participants, 21- to 65-years-old, were recruited. Participants were split into two groups of forty participants each, a placebo, and a L-carnitine Tartrate group. Seventy-three participants completed a maintenance exercise training program that culminated in a high-volume exercise challenge.
Compared to placebo, L-carnitine tartrate supplementation was able to improve perceived recovery and soreness ( = 0.021), and lower serum creatine kinase ( = 0.016). In addition, L-carnitine tartrate supplementation was able to blunt declines in strength and power compared to placebo following an exercise challenge. Two sub-analyses indicated that these results were independent of gender and age. Interestingly, serum superoxide dismutase levels increased significantly among those supplementing with L-carnitine tartrate.
These findings agree with previous observations among healthy adult subjects and demonstrate that L-carnitine tartrate supplementation beyond 35 days is beneficial for improving recovery and reducing fatigue following exercise across gender and age.
酒石酸左旋肉碱已被证明能改善运动员的短期恢复。然而，关于普通人群的长期效果的研究还很缺乏。
本随机双盲、安慰剂对照试验的主要目的是评估每天补充酒石酸左旋肉碱 5 周对恢复和疲劳的影响。
在这项研究中，招募了 80 名年龄在 21 至 65 岁之间的参与者。参与者被分为两组，每组 40 人，一组为安慰剂，一组为酒石酸左旋肉碱组。73 名参与者完成了一项维持性运动训练计划，最终进行了一项高容量的运动挑战。
与安慰剂相比，左旋肉碱补充剂能够改善主观恢复和酸痛（ = 0.021），并降低血清肌酸激酶（ = 0.016）。此外，与安慰剂相比，左旋肉碱补充剂能够在运动挑战后阻止力量和功率的下降。两项亚分析表明，这些结果与性别和年龄无关。有趣的是，补充左旋肉碱的血清超氧化物歧化酶水平显著升高。
这些发现与之前在健康成年受试者中的观察结果一致，并表明补充左旋肉碱超过 35 天对改善运动后的恢复和疲劳，具有性别和年龄普遍性的益处。
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