von Wettstein D
Philos Trans R Soc Lond B Biol Sci. 1977 Mar 21;277(955):235-43. doi: 10.1098/rstb.1977.0014.
The assembly of the synaptinemal complex in the ascomycete Neottiella was studied by three-dimensional reconstruction of a late zygotene nucleus. A single banded lateral component is formed between the two sister chromatids of each homologous chromosome prior to their pairing. The central regions are pre-assembled in organized form in folds of the granular part of the nucleolus and then converted into an amorphous transport form. The latter appears to move through the nucleoplasm to sites between the lateral components of synapsing homologous chromosomes. The central region material is reorganized into blocks with a recognizable central component and attached to one lateral component. The last step in the completion of the synaptinemal complex is the association of the free surface of the organized central region with the corresponding segment of the homologous lateral component. The findings are discussed in relation to mechanisms of chromosome pairing and chiasma formation.
通过对晚偶线期细胞核进行三维重建，研究了子囊菌新美座菌中联会复合体的组装过程。在每条同源染色体的两条姐妹染色单体配对之前，会在它们之间形成一条带状的侧生成分。中央区域在核仁颗粒部分的褶皱中以有组织的形式预先组装，然后转变为无定形的运输形式。后者似乎穿过核质，移动到正在联会的同源染色体侧生成分之间的位点。中央区域物质重新组织成具有可识别中央成分的块，并附着在一个侧生成分上。联会复合体完成的最后一步是有组织的中央区域的自由表面与同源侧生成分的相应片段结合。结合染色体配对和交叉形成的机制对这些发现进行了讨论。
