Dickens Chris, McGowan Linda, Percival Carol, Douglas Jane, Tomenson Barbara, Cotter Lawrence, Heagerty Anthony, Creed Francis
Department of Psychiatry, Manchester University, and the Department of Cardiology, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, U.K.
Psychosomatics. 2005 Nov-Dec;46(6):523-8. doi: 10.1176/appi.psy.46.6.523.
Depression following myocardial infarction is associated with a higher mortality rate. The authors studied 314 patients admitted to the hospital with a first myocardial infarction to assess whether cardiac failure after the infarction, which is also linked to a higher mortality rate, was predicted by psychosocial characteristics present before the myocardial infarction. One-fifth (20.7%) of the subjects met the ICD-10 criteria for depressive episode in the 1 month before the attack. Variables independently associated with worse cardiac failure after the myocardial infarction were greater age, a history of angina preceding the infarction, and a previous depressive episode. The impact of depression on postinfarction outcome may result from the influence of preinfarction depression on the degree of cardiac failure.
心肌梗死后的抑郁症与较高的死亡率相关。作者对314例首次因心肌梗死入院的患者进行了研究，以评估心肌梗死后与较高死亡率相关的心力衰竭是否可由心肌梗死前存在的社会心理特征预测。五分之一（20.7%）的受试者在发作前1个月符合ICD-10抑郁发作标准。与心肌梗死后更严重的心力衰竭独立相关的变量包括年龄较大、梗死前有心绞痛病史以及既往有抑郁发作史。抑郁症对梗死后结局的影响可能源于梗死前抑郁症对心力衰竭程度的影响。
