同手性取代双（二吡咯亚甲基）的双核锌（II）双螺旋配合物。

Dinuclear zinc(II) double-helicates of homochirally substituted bis(dipyrromethene)s.

作者信息

Wood Tabitha E, Ross Avena C, Dalgleish Nathan D, Power Erin D, Thompson Alison, Chen Xiaoming, Okamoto Yoshio

机构信息

Department of Chemistry, Dalhousie University, Halifax, Nova Scotia B3H 4J3, Canada.

出版信息

J Org Chem. 2005 Nov 25;70(24):9967-74. doi: 10.1021/jo051727e.

DOI:10.1021/jo051727e

PMID:16292829

Abstract

[structure: see text] A series of bis(dipyrromethene)s substituted with aromatic amide and aliphatic ester homochiral auxiliaries have been prepared and complexed with zinc(II) ions to form double-helical dinuclear complexes. CD analysis of the crude complexes revealed that the helicates formed in a diastereoselective manner. The helicates have been resolved into their constituent M and P helices by HPLC, indicating that the helical sense of the complexes is stable to racemization.

摘要

[结构：见正文] 已制备了一系列被芳香酰胺和脂肪族酯同手性助剂取代的双（二吡咯亚甲基）化合物，并使其与锌（II）离子络合形成双螺旋双核络合物。对粗络合物的圆二色性分析表明，螺旋络合物以非对映选择性方式形成。通过高效液相色谱法已将螺旋络合物拆分为其组成的M型和P型螺旋，这表明络合物的螺旋方向对消旋作用是稳定的。