Bayard Yves L, Ostermayer Stefan H, Sievert Horst
CardioVascular Center Frankfurt, Sankt Katharinen Seckbacher, Landstrasse 65, 60389 Frankfurt, Germany.
Expert Rev Cardiovasc Ther. 2005 Nov;3(6):1003-8. doi: 10.1586/14779072.3.6.1003.
Patients with atrial fibrillation are at an increased risk of having a cardioembolic stroke. Most of the thrombi responsible for these ischemic events originate in the left atrial appendage. Percutaneous occlusion of the left atrial appendage is a new approach to stroke prevention in patients with atrial fibrillation and contraindication for long-term warfarin treatment. Three different devices have been used so far: the PLAATO system, the WATCHMAN filter system and the Amplatzer septal occluder. Left atrial appendage occlusion using these devices is feasible and safe and has shown promising results. The risk of stroke in atrial fibrillation patients appears to be reduced.
心房颤动患者发生心源性栓塞性中风的风险增加。导致这些缺血性事件的血栓大多起源于左心耳。经皮封堵左心耳是心房颤动患者预防中风的一种新方法，也是长期华法林治疗的禁忌证。到目前为止，已经使用了三种不同的装置：PLAATO系统、WATCHMAN滤器系统和Amplatzer房间隔封堵器。使用这些装置封堵左心耳是可行且安全的，并已显示出有前景的结果。心房颤动患者的中风风险似乎有所降低。
