Grinda J M, Bricourt M O, Salvi S, Jouan J, Guillemain R, Deloche A, Fabiani J N
Service de chirurgie cardiovasculaire, HEGP, Paris.
Arch Mal Coeur Vaiss. 2005 Oct;98(10):1008-12.
Mechanical circulatory assistances now belong to the therapeutic stock in case of advanced heart failure. Their mainspring lays on the substitution of the failing left and/or right ventricle function with a pump. The goal being to maintain or restore the system main functions. Their main indication is a bridge to transplant mechanical circulatory assistance, allowing the patient to await transplantation. However, indications for definitive implantation appear in case of transplantation counter indication, mechanical circulatory assistances already emerging as a possible alternative to transplantation. For over 10 years, we have used pulsatile flow assistances, either with pneumatic ventricles or electro-mechanic implantable left ventricles. We henceforth observe the development of a new generation of implantable assistance providing a non-pulsatile flow. These are axial pumps. We evaluated the first model, the DeBakey axial pump which became the most used axial pump worldwide. We now observe the development of other axial pumps as well as the development of new implantable centrifugal pumps.
对于晚期心力衰竭患者，机械循环辅助装置现已成为治疗手段之一。其核心在于用泵替代衰竭的左心室和/或右心室功能，目的是维持或恢复系统的主要功能。其主要适应证是作为移植的桥梁，即机械循环辅助装置可让患者等待移植。然而，在存在移植禁忌证的情况下，就会出现永久性植入的适应证，机械循环辅助装置已成为移植的一种可能替代方案。十多年来，我们一直使用搏动性血流辅助装置，包括气动心室或可植入式电动左心室。此后，我们观察到新一代提供非搏动性血流的可植入式辅助装置的发展，即轴流泵。我们评估了首个型号——德巴基轴流泵，它成为全球使用最广泛的轴流泵。我们现在还观察到其他轴流泵的发展以及新型可植入式离心泵的发展。
