Suppr超能文献

与敌人共舞:单纯疱疹病毒与树突状细胞的相互作用

Dancing with the enemy: the interplay of herpes simplex virus with dendritic cells.

作者信息

Novak N, Peng W M

机构信息

Department of Dermatology, University of Bonn, Germany.

出版信息

Clin Exp Immunol. 2005 Dec;142(3):405-10. doi: 10.1111/j.1365-2249.2005.02927.x.

Abstract

Summary Herpes simplex virus (HSV) represents a smart pathogen, which displays both lytic and latent modes of interaction with its natural human host. In order to be optimally equipped for immune evasion and to reply to any attacks of the host during reactivation, HSV has developed a multitude of cleverly devised defence strategies. Dendritic cells (DC) as antigen-presenting cells located at the border zones of the body and the environment have been shown to play a crucial role as one of the first cells interacting with HSV beside epithelial cells, on one hand, and as important controllers of the viral spreading on the other hand. Here, we provide a research update about the interaction of HSV with DC and summarize the latest proceedings in this field.

摘要

摘要 单纯疱疹病毒(HSV)是一种智能病原体,它与人类天然宿主呈现出裂解和潜伏两种相互作用模式。为了在免疫逃避方面具备最佳能力,并在病毒重新激活时应对宿主的任何攻击,HSV已经制定了多种精心设计的防御策略。树突状细胞(DC)作为位于身体与外界交界区域的抗原呈递细胞,一方面已被证明是除上皮细胞外最早与HSV相互作用的细胞之一,发挥着关键作用;另一方面,它也是病毒传播的重要控制者。在此,我们提供关于HSV与DC相互作用的研究进展更新,并总结该领域的最新研究成果。

相似文献

4
Recognition of herpes simplex viruses: toll-like receptors and beyond.单纯疱疹病毒的识别: toll 样受体及其他。
J Mol Biol. 2014 Mar 20;426(6):1133-47. doi: 10.1016/j.jmb.2013.11.012. Epub 2013 Nov 19.
7
Langerhans cells and viral immunity.朗格汉斯细胞与病毒免疫。
Eur J Immunol. 2008 Sep;38(9):2377-85. doi: 10.1002/eji.200838521.
10
The Toll of herpes simplex virus infection.单纯疱疹病毒感染的危害。
Trends Microbiol. 2004 Aug;12(8):353-6. doi: 10.1016/j.tim.2004.06.001.

引用本文的文献

4
Pathobiology and treatment of viral keratitis.病毒性角膜炎的发病机制与治疗。
Exp Eye Res. 2021 Apr;205:108483. doi: 10.1016/j.exer.2021.108483. Epub 2021 Feb 6.
6
The Role of C21orf91 in Herpes Simplex Virus Keratitis.C21orf91在单纯疱疹病毒性角膜炎中的作用
Medicina (Kaunas). 2019 Nov 20;55(12):753. doi: 10.3390/medicina55120753.

本文引用的文献

8
Toll-like receptor signalling.Toll样受体信号传导
Nat Rev Immunol. 2004 Jul;4(7):499-511. doi: 10.1038/nri1391.
10
Recognition of single-stranded RNA viruses by Toll-like receptor 7.Toll样受体7对单链RNA病毒的识别
Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5598-603. doi: 10.1073/pnas.0400937101. Epub 2004 Mar 19.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验