Haimovich Beatrice, Venkatesan Malabi M
Department of Surgery and the Cancer Institute of New Jersey, RWJMS-UMDNJ, New Brunswick, NJ 08903, USA.
Microbes Infect. 2006 Feb;8(2):568-77. doi: 10.1016/j.micinf.2005.08.002. Epub 2005 Oct 7.
Shigella and Salmonella kill host cells and trigger inflammatory responses by mechanisms that are not fully understood. The goal of this review is to reevaluate key observations reported over the past 15 years and, whenever possible, to provide a chronological perspective as to how our understanding of the pathways by which Shigella and Salmonella kill host cells has evolved.