Frost F, Taylor V, Fries E
Center for Health and Population Research, Lovelace Medical Foundation, Albuquerque, N.M. 87108.
J Natl Cancer Inst. 1992 Jun 17;84(12):957-62. doi: 10.1093/jnci/84.12.957.
The cancer incidence for all sites has been reported to be lower in Native Americans than in White Americans. Concerns have been expressed, however, that the observed low incidence may be a result of inaccurate reporting of race.
The objective of this study was to investigate the extent to which racial misclassification may contribute to the observed low cancer incidence among Native Americans.
A registry of individuals eligible to receive medical services funded by the Indian Health Service was linked by computer to the Puget Sound Surveillance, Epidemiology, and End Results (SEER) cancer registry.
Only 137 (60%) of the patients with invasive cancer registered with the Indian Health Service and for whom race was recorded were identified as Native Americans in the SEER registry. Similarly, 55 (69%) of 80 in situ cervical cancer case patients were classified as Native American. A strong association was observed between Native-American blood quantum level and racial misclassification.
The results of this study indicate that the observed low cancer incidence in Native Americans relative to Whites in the northwest United States is at least partially attributable to racial misclassification in the SEER cancer registry.
据报道，美洲原住民所有部位的癌症发病率低于美国白人。然而，有人担心观察到的低发病率可能是种族报告不准确的结果。
本研究的目的是调查种族错误分类在多大程度上可能导致观察到的美洲原住民癌症低发病率。
一个有资格接受印第安卫生服务局资助的医疗服务的个人登记册通过计算机与普吉特海湾监测、流行病学和最终结果（SEER）癌症登记处相链接。
在印第安卫生服务局登记且记录了种族的浸润性癌患者中，只有137名（60%）在SEER登记处被确定为美洲原住民。同样，80例原位宫颈癌患者中有55例（69%）被归类为美洲原住民。观察到美洲原住民血统比例与种族错误分类之间存在密切关联。
本研究结果表明，在美国西北部，观察到的美洲原住民相对于白人的低癌症发病率至少部分归因于SEER癌症登记处的种族错误分类。
