Casson Alan G, van Lanschot J Jan B
Department of Surgery, Division of Thoracic & Esophageal Surgery, Dalhousie University and the QE II Health Sciences Centre, 1278 Tower Road, Halifax, Nova Scotia, Canada B3H 2Y9.
J Surg Oncol. 2005 Dec 1;92(3):262-6. doi: 10.1002/jso.20368.
Once considered an uncommon malignancy, primary esophageal adenocarcinoma has increased steadily in incidence over the past three decades. Despite advances in multimodality therapy, the prognosis for this tumor is generally poor. Surgical resection and reconstruction of the upper gastrointestinal tract is the current standard of care for localized esophageal cancer, but despite advances in perioperative care, still remains a relatively high-risk surgical procedure. Increasing numbers of reports published over the past decade have documented a clear volume-outcome relationship for several complex surgical procedures, and in particular for esophagectomy. The clinical implications of this association are reviewed in this section.
原发性食管腺癌曾被认为是一种罕见的恶性肿瘤，在过去三十年中其发病率稳步上升。尽管多模式治疗取得了进展，但这种肿瘤的预后总体较差。上消化道的手术切除和重建是局限性食管癌目前的标准治疗方法，但尽管围手术期护理有所进步，它仍然是一种风险相对较高的外科手术。在过去十年中，越来越多的报告记录了几种复杂外科手术，特别是食管切除术，存在明确的手术量-预后关系。本节将对这种关联的临床意义进行综述。
