Gencur Sara J, Rimnac Clare M, Kurtz Steven M
Musculoskeletal Mechanics and Materials Laboratories, Department of Mechanical and Aerospace Engineering, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH 44106-7222, USA.
Biomaterials. 2006 Mar;27(8):1550-7. doi: 10.1016/j.biomaterials.2005.09.010. Epub 2005 Nov 21.
To prolong the life of total joint replacements, highly crosslinked ultra-high molecular weight polyethylenes (UHMWPEs) have been introduced to improve the wear resistance of the articulating surfaces. However, there are concerns regarding the loss of ductility and potential loss in fatigue crack propagation (FCP) resistance. The objective of this study was to evaluate the effects of gamma radiation-induced crosslinking with two different post-irradiation thermal treatments on the FCP resistance of UHMWPE. Two highly crosslinked and one virgin UHMWPE treatment groups (ram-extruded, orthopedic grade, GUR 1050) were examined. For the two highly crosslinked treatment groups, UHMWPE rods were exposed to 100 kGy and then underwent post-irradiation thermal processing either above the melt temperature or below the melt temperature (2 h-150 degrees C, 110 degrees C). Compact tension specimens were cyclically loaded to failure and the fatigue crack growth rate, da/dN, vs. cyclic stress intensity factor, DeltaK, behavior was determined and compared between groups. Scanning electron microscopy was used to examine fracture surface characteristics. Crosslinking was found to decrease the ability of UHMWPE to resist crack inception and propagation under cyclic loading. The findings also suggested that annealing as a post-irradiation treatment may be somewhat less detrimental to FCP resistance of UHMWPE than remelting. Scanning electron microscopy examination of the fracture surfaces demonstrated that the virgin treatment group failed in a more ductile manner than the two highly crosslinked treatment groups.
为延长全关节置换物的使用寿命,已引入高度交联的超高分子量聚乙烯(UHMWPE)以提高关节表面的耐磨性。然而,人们担心其延展性的丧失以及疲劳裂纹扩展(FCP)抗性的潜在损失。本研究的目的是评估γ辐射诱导交联以及两种不同的辐照后热处理对UHMWPE的FCP抗性的影响。研究了两个高度交联的组和一个原始UHMWPE处理组(冲压挤出,矫形级,GUR 1050)。对于两个高度交联的处理组,UHMWPE棒材先接受100 kGy的辐射,然后在高于或低于熔融温度(2小时-150摄氏度,110摄氏度)的条件下进行辐照后热处理。紧凑拉伸试样循环加载直至失效,并测定疲劳裂纹扩展速率da/dN与循环应力强度因子ΔK之间的关系,并在组间进行比较。使用扫描电子显微镜检查断口表面特征。发现交联会降低UHMWPE在循环载荷下抵抗裂纹萌生和扩展的能力。研究结果还表明,作为辐照后处理的退火对UHMWPE的FCP抗性的损害可能比重新熔融要小一些。对断口表面的扫描电子显微镜检查表明,原始处理组的失效方式比两个高度交联的处理组更具韧性。