Freeman Matthew
MRC Laboratory of Molecular Biology, Cambridge, UK.
Curr Biol. 2005 Nov 22;15(22):R924-6. doi: 10.1016/j.cub.2005.10.062.
The retina provides an example of a fundamental property of developing cells: cell fate decisions are stable. A recent paper reports a double negative feedback loop that leads to bistable fate decisions in the colour-detecting photoreceptors of Drosophila.
细胞命运决定是稳定的。最近的一篇论文报道了一个双负反馈回路,该回路在果蝇的颜色检测光感受器中导致双稳态命运决定。