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[辐射与光照联合作用下神经内分泌换能器的可塑性]

[Plasticity of neuroendocrine transducers under the combined influence of the radiation and light exposure].

作者信息

Gerasimov A V, Logvinov S V

出版信息

Radiats Biol Radioecol. 2005 Sep-Oct;45(5):599-604.

Abstract

The structural changes of neurons of the rat hypothalamic supraoptic (SON) and of paraventricular (PVN) nucleus after 48 h of bright light exposure, of 5 Gy whole-body X-irradiation and of their combination subjected to the analysis by means of light-optic and of electron microscopy for the estimation of radimodificated effect of light exposure lasted 24 h a day and plasticity of neuroendocrine transducers interacted with the optic sensory system. The structural changes of neurons of the SON after combined action are less considerable and more prolonged in comparison with the PVN that loas defermined by their direct connection with the optic sensory system via the retinohypothalamic tract.

摘要

通过光学显微镜和电子显微镜分析,研究了大鼠下丘脑视上核(SON)和室旁核(PVN)神经元在每天持续24小时强光照射48小时、5 Gy全身X射线照射及其联合作用后的结构变化,以评估强光照射的辐射修饰效应以及与视觉感觉系统相互作用的神经内分泌换能器的可塑性。与PVN相比,联合作用后SON神经元的结构变化较小且持续时间更长,这是由它们通过视网膜下丘脑束与视觉感觉系统的直接连接所决定的。

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