Kandler Karl, Thiels Edda
Nat Neurosci. 2005 Dec;8(12):1633-4. doi: 10.1038/nn1205-1633.
Immature neurons in many brain regions are electrically coupled through gap junctions, which are lost as chemical synaptic transmission matures. This developmental uncoupling is now shown to require NMDA receptor activation.
许多脑区中的未成熟神经元通过缝隙连接形成电耦合,随着化学突触传递的成熟,这种耦合会消失。现在研究表明,这种发育过程中的去耦合需要NMDA受体激活。