脱髓鞘疾病所致视神经炎的视网膜电图C波和视觉诱发电位

C wave of electroretinogram and visual evoked response in optic neuritis due to demyelinating diseases.

作者信息

Moschos M, Brouzas D

机构信息

Laboratory of Electrophysiology, Athens University Eye Clinic, Greece.

出版信息

Ophthalmologica. 1992;204(3):149-55. doi: 10.1159/000310284.

DOI:10.1159/000310284

PMID:1630764

Abstract

In 21 consecutive cases with unilateral optic neuritis due to demyelinating disease, ERG, C wave of ERG and VER were recorded and studied in both eyes. Also 8 cases suffering from optic atrophy due to trauma or glaucoma were included. The analysis of data shows that the C-wave is significantly diminished in both eyes, namely the affected and the sound, in the cases of optic neuritis. Also in comparison to VER, C wave has a comparative probability in diagnosing optic neuritis due to demyelinating disease. The C wave of ERG is normal in the cases of optic atrophy. The mechanism of C wave involvement during the course of demyelinating disease may be related with an abnormality of the ionic homeostasis of the subretinal space.

摘要

在21例因脱髓鞘疾病导致单侧视神经炎的连续病例中，对双眼进行了视网膜电图（ERG）、ERG的C波和视觉诱发电位（VER）的记录与研究。另外还纳入了8例因外伤或青光眼导致视神经萎缩的病例。数据分析表明，在视神经炎病例中，患眼和健眼的C波均显著降低。而且与VER相比，C波在诊断脱髓鞘疾病所致视神经炎方面具有相对较高的概率。在视神经萎缩病例中，ERG的C波是正常的。脱髓鞘疾病过程中C波受累的机制可能与视网膜下间隙离子稳态异常有关。