Miyazaki I
Department of Ophthalmology, School of Medicine, Chiba University, Japan.
Nippon Ganka Gakkai Zasshi. 1991 Oct;95(10):995-1003.
Optic neuritis in childhood caused by demyelinating disease is very rare, and its effect on visual function has not been well documented. The visual function of 11 patients treated in the last 11 years was retrospectively studied and the results were compared with 15 cases of optic neuritis of unknown etiology. Optic neuritis in children with demyelinating disease was characterized as follows. 1. abnormal visual evoked cortical potentials (VECP) and color vision were found not only in the affected eye but also in the non-affected fellow eye, 2. VECPs became normal long after the recovery of visual acuity, 3. full recovery of visual function took longer, 4. at onset, vision was more severely affected, but showed a good outcome. These findings provide useful information to make a diagnosis of multiple sclerosis even at the first attack of optic neuritis.
由脱髓鞘疾病引起的儿童视神经炎非常罕见,其对视觉功能的影响尚无充分记录。回顾性研究了过去11年中接受治疗的11例患者的视觉功能,并将结果与15例病因不明的视神经炎病例进行了比较。脱髓鞘疾病患儿的视神经炎具有以下特征。1. 不仅患眼,而且未受影响的对侧眼也发现视觉诱发电位(VECP)异常和色觉异常;2. 视力恢复很久后VECP才恢复正常;3. 视觉功能完全恢复所需时间更长;4. 发病时,视力受影响更严重,但预后良好。这些发现为即使在视神经炎首次发作时诊断多发性硬化症提供了有用信息。