Dente Christopher J, Feliciano David V, Rozycki Grace S, Wyrzykowski Amy D, Nicholas Jeffrey M, Salomone Jeffrey P, Ingram Walter L
Emory University, Grady Memorial Hospital, 69 Jesse Hill Dr., Atlanta, GA 30303, USA.
Am J Surg. 2005 Dec;190(6):830-5. doi: 10.1016/j.amjsurg.2005.05.050.
Recent series have reported that the mortality rate of open pelvic fractures has decreased to < 10%. These injuries are often associated with intra-abdominal visceral damage, although few series have documented the prognostic significance of this injury complex.
A retrospective review in an urban level I trauma center of all patients who sustained open pelvic fracture between 1995 and 2004.
Forty-four patients were identified as having sustained open pelvic fracture. Average Injury Severity Score was 30, with 77% of patients having a score > or = 16. Overall mortality was 45% (n = 20): 11 early deaths and 9 late deaths at an average of 17 days. Vertical shear injuries, although rare, were universally fatal. Other risk factors for overall mortality included revised trauma score, Injury Severity Score, transfusion requirement, Faringer zones I or II injury, Gustilo grade III soft tissue injury, need for therapeutic angiography, and presence of intra-abdominal injury, the latter of which conferred 89% mortality. Risk factors for late deaths also included pelvic sepsis, which occurred in 5 patients and was fatal in 3 (60%).
The morbidity of open pelvic fractures remains high. Associated intra-abdominal injury or active arterial bleeding requiring therapeutic angiography is associated with a grim prognosis. There is a continuing need for new therapeutic approaches to this injury complex.
近期系列报道称开放性骨盆骨折的死亡率已降至<10%。这些损伤常伴有腹腔内脏器损伤,尽管很少有系列报道记录这种损伤组合的预后意义。
对一家城市一级创伤中心1995年至2004年间所有发生开放性骨盆骨折的患者进行回顾性研究。
确定44例患者发生了开放性骨盆骨折。平均损伤严重度评分为30分,77%的患者评分≥16分。总体死亡率为45%(n = 20):11例早期死亡和9例晚期死亡,平均死亡时间为17天。垂直剪切伤虽然罕见,但无一例外均为致命伤。总体死亡的其他危险因素包括修正创伤评分、损伤严重度评分、输血需求、法林格I区或II区损伤、古斯蒂洛III级软组织损伤、需要进行治疗性血管造影以及存在腹腔内损伤,后者的死亡率为89%。晚期死亡的危险因素还包括骨盆脓毒症,5例患者发生骨盆脓毒症,3例(60%)死亡。
开放性骨盆骨折的发病率仍然很高。伴有腹腔内损伤或需要进行治疗性血管造影的活动性动脉出血与预后不良相关。对于这种损伤组合,持续需要新的治疗方法。