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利用国家创伤数据库分析骨盆骨折中泌尿生殖系统损伤的发病率和死亡率

Genitourinary injuries in pelvic fracture morbidity and mortality using the National Trauma Data Bank.

作者信息

Bjurlin Marc A, Fantus Richard J, Mellett Michele M, Goble Sandra M

机构信息

Section of Trauma and Surgical Critical Care, Department of Surgery, Advocate Illinois Masonic Medical Center, Chicago, Illinois 60657, USA.

出版信息

J Trauma. 2009 Nov;67(5):1033-9. doi: 10.1097/TA.0b013e3181bb8d6c.

Abstract

BACKGROUND

Pelvic fractures from blunt force trauma place the bladder and urethra at risk for injury, often resulting in significant complications. We sought to compare morbidity, mortality, and health care resource utilization in patients with and without genitourinary injuries (GUI) associated with pelvic fractures.

METHODS

In this retrospective study of patients with blunt force pelvic fractures, the incidence of GUI, initial emergency department data, mechanism of injury, morbidity, health care resource utilization, associated injuries, discharge disposition, and mortality were investigated using chi tests for categorical variables and Student's t test for continuous variables comparing pelvic fractures with and without GUI. Multiple logistic regression analysis was used to detect significant predictors of mortality.

RESULTS

Of the 31,380 patients with pelvic fractures, 1,444 had GUI. Men more commonly sustained pelvic fractures with GUI than women (66.14% vs. 33.86%). The incidence of urogenital, bladder, and urethral injuries for men and women was 5.34%, 3.41%, 1.54%, and 3.62%, 3.37%, 0.15%, respectively. Patients with GUI remained hospitalized longer (median 10 vs. 6 d, p < 0.001), had more intensive care unit stay days (median 3 vs. 1 d, p < 0.001), were less often discharged home (31.02% vs. 42.82%), and had an increased mortality rate (13.99% vs. 8.08%, p < 0.001) when compared with patients without GUI. Motor vehicle collisions were the most common mechanism of injury for all pelvic fractures. Spleen and liver were the most commonly injured abdominal organs associated with pelvic fractures as a whole. Pelvic fractures with GUI were more likely to result in associated injuries of the bowel, and reproductive organs. Although GUI was not found to be an independent predictor of mortality, age >or=65 years, initial systolic blood pressure in the emergency department 0 mm Hg to 90 mm Hg, Injury Severity Score >or=25, Glasgow coma score of <or=8, and female gender were independent predictors of mortality.

CONCLUSION

Patients sustaining a pelvic fracture with GUI have an increase in morbidity. Although GUI was not an independent predictor of mortality, patients who sustained a pelvic fracture with GUI had a greater number of concomitant injuries resulting in an increase in overall mortality compared with those without an associated GUI.

摘要

背景

钝性暴力创伤导致的骨盆骨折会使膀胱和尿道面临受伤风险,常引发严重并发症。我们试图比较合并和未合并与骨盆骨折相关的泌尿生殖系统损伤(GUI)患者的发病率、死亡率及医疗资源利用情况。

方法

在这项对钝性暴力骨盆骨折患者的回顾性研究中,采用卡方检验分析分类变量,采用学生t检验分析连续变量,以调查GUI的发生率、急诊科初始数据、损伤机制、发病率、医疗资源利用情况、相关损伤、出院处置及死亡率,比较合并和未合并GUI的骨盆骨折患者。采用多因素逻辑回归分析确定死亡率的显著预测因素。

结果

在31380例骨盆骨折患者中,1444例合并GUI。男性合并GUI的骨盆骨折发生率高于女性(66.14%对33.86%)。男性和女性的泌尿生殖系统、膀胱及尿道损伤发生率分别为5.34%、3.41%、1.54%和3.62%、3.37%、0.15%。与未合并GUI的患者相比,合并GUI的患者住院时间更长(中位数10天对6天,p<0.001),重症监护病房停留天数更多(中位数3天对1天,p<0.001),出院回家的比例更低(31.02%对42.82%),死亡率更高(13.99%对8.08%,p<0.001)。机动车碰撞是所有骨盆骨折最常见的损伤机制。脾脏和肝脏是与骨盆骨折整体相关的最常受伤的腹部器官。合并GUI的骨盆骨折更易导致肠道及生殖器官的相关损伤。虽然未发现GUI是死亡率的独立预测因素,但年龄≥65岁、急诊科初始收缩压0mmHg至90mmHg、损伤严重度评分≥25、格拉斯哥昏迷评分≤8及女性性别是死亡率的独立预测因素。

结论

合并GUI的骨盆骨折患者发病率增加。虽然GUI不是死亡率的独立预测因素,但与未合并GUI的患者相比,合并GUI的骨盆骨折患者伴随损伤更多,导致总体死亡率增加。

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