Horváth G, Tolvaj G, Dávid K
I. Belgyógyászati Osztály, BM Központi Kórház és Intézményei, Budapest.
Orv Hetil. 1992 Jul 5;133 Suppl 1:39-44.
The data on hepatitis delta virus and the liver diseases caused by it are reviewed. The findings of hepatitis B and D virus markers in 118 hepatitis B virus seropositive patients suffering from histologically confirmed chronic liver disease are reported. The prevalence of hepatitis delta virus infection was 13.56% of these cases, while active hepatitis delta virus replication was proved in 6 cases of them. Based on their findings, the role of hepatitis delta virus in the progression of chronic liver diseases is concluded, similarly to data published earlier. The importance of repeated, detailed virus-serological and histological examinations is stressed, especially in the cases in which the progression of liver disease are detected. The authors suggest that HBsAg--IgM complex seropositivity in patients suffering from anti-delta seropositive chronic liver disease supports active hepatitis delta virus infection.
本文回顾了丁型肝炎病毒及其所致肝脏疾病的数据。报告了118例经组织学确诊为慢性肝病的乙肝病毒血清学阳性患者中乙肝和丁型病毒标志物的检测结果。这些病例中丁型肝炎病毒感染的患病率为13.56%，其中6例证实有丁型肝炎病毒活跃复制。基于这些发现，得出丁型肝炎病毒在慢性肝病进展中的作用，这与早期发表的数据相似。强调了反复、详细的病毒血清学和组织学检查的重要性，特别是在检测到肝病进展的病例中。作者认为，抗丁型血清学阳性的慢性肝病患者中HBsAg-IgM复合物血清学阳性支持丁型肝炎病毒的活跃感染。
