用重组α-干扰素治疗慢性病毒性肝炎
[Treatment of chronic viral hepatitis with recombinant interferon-alfa].
作者信息
Peter F
机构信息
IV. sz. Egyetemi Belgyógyászati Klinika, Universität Wien, Austria.
出版信息
Orv Hetil. 1992 Jul 5;133 Suppl 1:66-71.
PMID:1630806
Abstract
The antiviral treatment with alfa-interferon is the first proven therapeutic possibility in chronic viral hepatitis. The rate of improvement to alfa-interferon ranges between 15-40% depending on the type of hepatitis. The optimal dose is 5 MU/day three times a week for 6 months in chronic hepatitis B, while 3 MU/day three times a week for months in chronic hepatitis C. Results of therapy can be improved using combination treatment in selected cases.
摘要
用α干扰素进行抗病毒治疗是慢性病毒性肝炎中首个经证实的治疗方法。根据肝炎类型的不同，使用α干扰素治疗后病情改善的比例在15%至40%之间。慢性乙型肝炎的最佳剂量是每周三次，每次500万单位，持续6个月；而慢性丙型肝炎的最佳剂量是每周三次，每次300万单位，持续数月。在部分病例中，联合治疗可改善治疗效果。
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