Novokshonova I V, Zelenskaia O I, Gol'dberg I E, Kozlikhin B A, Shneĭderman L V
Antibiot Khimioter. 2005;50(2-3):30-2.
The results of the Shigella antibiotic susceptibility assay within 1995-2002 are presented. 1472 cultures from 1158 patients with intestinal infections and bacteria carriers were isolated. The isolates were tested for their susceptibility to tetracycline, chloramphenicol, gentamicin, kanamycin, ampicillin and ofloxacin. It was shown that S. flexneri and S. sonnei were resistant to tetracycline. The S. flexneri isolates were highly resistant to chloramphenicol (73.3 to 96.0%) while resistance to it in the isolates of S. sonnei varied from 7.7 to 88.5%. In this connection the Levin medium with tetracycline was used to increase the Shigella isolation. In the study of the culture media efficiency with respect to isolation of Shigella it was observed that the Levin medium with tetracycline provided higher rates of S. flexneri and S. sonnei isolation (2.3- and 1.7-fold increase respectively) vs. the Shigella isolation on the Ploskirev medium without the antibiotic.
本文展示了1995 - 2002年间志贺氏菌抗生素敏感性检测的结果。从1158例肠道感染患者和细菌携带者中分离出1472株培养物。对分离菌株进行了四环素、氯霉素、庆大霉素、卡那霉素、氨苄青霉素和氧氟沙星的敏感性检测。结果显示，福氏志贺菌和宋内志贺菌对四环素耐药。福氏志贺菌分离株对氯霉素高度耐药（73.3%至96.0%），而宋内志贺菌分离株对氯霉素的耐药率在7.7%至88.5%之间。因此，使用含四环素的列文培养基来提高志贺氏菌的分离率。在研究培养基对志贺氏菌分离的效率时发现，与不含抗生素的普洛斯基列夫培养基相比，含四环素的列文培养基能提高福氏志贺菌和宋内志贺菌的分离率（分别提高2.3倍和1.7倍）。
