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镰状细胞病患者出现皮肤坏死的显微镜下多动脉炎。

Microscopic polyarteritis presenting with skin necrosis in a patient with sickle-cell disease.

作者信息

Dawe S A, Powell S E, Short K A, Salisbury J, Roberts J, Creamer D

机构信息

Department of Dermatology, Kings College Hospital, Denmark Hill, London, SE5 9RS, UK.

出版信息

Clin Exp Dermatol. 2006 Jan;31(1):60-2. doi: 10.1111/j.1365-2230.2005.01950.x.

DOI:10.1111/j.1365-2230.2005.01950.x
PMID:16309484
Abstract

A 20-year-old Caribbean woman with sickle cell anaemia was admitted with a 4-day history of fever and a painful swollen right ankle. She rapidly developed skin necrosis. The differential diagnosis is discussed. This case illustrates the difficulty in identifying the cause of cutaneous necrosis in an acutely ill patient. In our patient, histopathology implicated a vasculitic process, which was subsequently identified as a manifestation of microscopic polyarteritis.

摘要

一名20岁患有镰状细胞贫血的加勒比女性因发热4天和右踝关节疼痛肿胀入院。她迅速出现皮肤坏死。讨论了鉴别诊断。该病例说明了在急症患者中确定皮肤坏死原因的困难。在我们的患者中,组织病理学提示为血管炎过程,随后被确定为显微镜下多动脉炎的一种表现。

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