松弛素及松弛素相关肽生物学作用的新见解 - Suppr

New Insights into biological roles of relaxin and relaxin-related peptides.

作者信息

Park Jae-Il, Chang Chia Lin, Hsu Sheau Yu Teddy

机构信息

Division of Reproductive Biology, Department of Obstetrics and Gynecology, School of Medicine, Stanford University, CA 94305-5317, USA.

出版信息

Rev Endocr Metab Disord. 2005 Dec;6(4):291-6. doi: 10.1007/s11154-005-6187-x.

DOI:10.1007/s11154-005-6187-x

PMID:16311947

Abstract

摘要

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New Insights into biological roles of relaxin and relaxin-related peptides.

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Beneficial effects of relaxin on motility characteristics of stored boar spermatozoa.

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Evolution of the relaxin/insulin-like gene family in anthropoid primates.

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The emerging role of relaxin as a novel therapeutic pathway in the treatment of chronic kidney disease.

Am J Physiol Regul Integr Comp Physiol. 2013 Sep 15;305(6):R559-65. doi: 10.1152/ajpregu.00528.2012. Epub 2013 Jul 24.

Relationship of relaxin hormone and thumb carpometacarpal joint arthritis.

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New insight into the transcriptional regulation of vascular endothelial growth factor expression in the endometrium by estrogen and relaxin.

Ann N Y Acad Sci. 2005 May;1041:233-47. doi: 10.1196/annals.1282.037.

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The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7.

J Biol Chem. 2005 Apr 8;280(14):14051-6. doi: 10.1074/jbc.M500030200. Epub 2005 Feb 4.

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J Clin Endocrinol Metab. 2005 Jan;90(1):516-21. doi: 10.1210/jc.2004-0130. Epub 2004 Oct 13.

Vascular endothelial growth factor: basic science and clinical progress.

Endocr Rev. 2004 Aug;25(4):581-611. doi: 10.1210/er.2003-0027.

Genetic targeting of relaxin and insulin-like factor 3 receptors in mice.

Endocrinology. 2004 Oct;145(10):4712-20. doi: 10.1210/en.2004-0515. Epub 2004 Jul 15.

Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo.

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New Insights into biological roles of relaxin and relaxin-related peptides.

Rev Endocr Metab Disord. 2005 Dec;6(4):291-6. doi: 10.1007/s11154-005-6187-x.

Relaxin's physiological roles and other diverse actions.

Endocr Rev. 2004 Apr;25(2):205-34. doi: 10.1210/er.2003-0013.

Relaxin peptides are new global players.

Trends Endocrinol Metab. 2002 Oct;13(8):343-8. doi: 10.1016/s1043-2760(02)00664-1.

Relaxin as a new hormone.

Endocr Rev. 1982 Winter;3(1):62-90. doi: 10.1210/edrv-3-1-62.

Adv Exp Med Biol. 2007;612:49-64. doi: 10.1007/978-0-387-74672-2_5.

Relaxin physiology in the female reproductive tract during pregnancy.

Adv Exp Med Biol. 2007;612:34-48. doi: 10.1007/978-0-387-74672-2_4.

Biology of primate relaxin: a paracrine signal in early pregnancy?

Reprod Biol Endocrinol. 2004 Jun 16;2:36. doi: 10.1186/1477-7827-2-36.

Relaxin family peptide receptors--from orphans to therapeutic targets.

Drug Discov Today. 2008 Aug;13(15-16):640-51. doi: 10.1016/j.drudis.2008.04.002. Epub 2008 Jun 6.

Comparison of signaling pathways activated by the relaxin family peptide receptors, RXFP1 and RXFP2, using reporter genes.

J Pharmacol Exp Ther. 2007 Jan;320(1):281-90. doi: 10.1124/jpet.106.113225. Epub 2006 Oct 25.

Relaxin-like peptides in cancer.

Int J Cancer. 2003 Nov 20;107(4):513-9. doi: 10.1002/ijc.11424.

引用本文的文献

Genomic and gene expression associations to morphology of a sexual ornament in the chicken.

G3 (Bethesda). 2022 Aug 25;12(9). doi: 10.1093/g3journal/jkac174.

Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function.

Front Endocrinol (Lausanne). 2021 Mar 11;12:649880. doi: 10.3389/fendo.2021.649880. eCollection 2021.

Circulating Relaxin-1 Level Is a Surrogate Marker of Myocardial Fibrosis in HFrEF.

Front Physiol. 2019 Jun 4;10:690. doi: 10.3389/fphys.2019.00690. eCollection 2019.

Relaxin as a hormonal aid to evaluate pregnancy and pregnancy loss in bottlenose dolphins (Tursiops truncatus).

Gen Comp Endocrinol. 2017 Feb 1;242:24-29. doi: 10.1016/j.ygcen.2015.12.024. Epub 2015 Dec 24.

Serum relaxin levels as a novel biomarker for detection of acute myocardial infarction.

Int J Clin Exp Med. 2015 Sep 15;8(9):16937-40. eCollection 2015.

Beneficial effects of relaxin on motility characteristics of stored boar spermatozoa.

Reprod Biol Endocrinol. 2015 Mar 31;13:24. doi: 10.1186/s12958-015-0021-4.

Evolution of the relaxin/insulin-like gene family in anthropoid primates.

Genome Biol Evol. 2014 Mar;6(3):491-9. doi: 10.1093/gbe/evu023.

Sex-steroid regulation of relaxin receptor isoforms (RXFP1 & RXFP2) expression in the patellar tendon and lateral collateral ligament of female WKY rats.

Int J Med Sci. 2014 Jan 9;11(2):180-91. doi: 10.7150/ijms.6283. eCollection 2014.

The emerging role of relaxin as a novel therapeutic pathway in the treatment of chronic kidney disease.

Am J Physiol Regul Integr Comp Physiol. 2013 Sep 15;305(6):R559-65. doi: 10.1152/ajpregu.00528.2012. Epub 2013 Jul 24.

Relationship of relaxin hormone and thumb carpometacarpal joint arthritis.

Clin Orthop Relat Res. 2014 Apr;472(4):1130-7. doi: 10.1007/s11999-013-2960-4.

本文引用的文献

Relaxin reverses cardiac and renal fibrosis in spontaneously hypertensive rats.

Hypertension. 2005 Aug;46(2):412-8. doi: 10.1161/01.HYP.0000171930.00697.2f. Epub 2005 Jun 20.

The use of relaxin improves healing in injured muscle.

Ann N Y Acad Sci. 2005 May;1041:395-7. doi: 10.1196/annals.1282.060.

New insight into the transcriptional regulation of vascular endothelial growth factor expression in the endometrium by estrogen and relaxin.

Ann N Y Acad Sci. 2005 May;1041:233-47. doi: 10.1196/annals.1282.037.

Genetic targeting of relaxin and insl3 signaling in mice.

Ann N Y Acad Sci. 2005 May;1041:82-90. doi: 10.1196/annals.1282.012.

Relaxin and prostaglandin E(2) regulate interleukin 11 during human endometrial stromal cell decidualization.

J Clin Endocrinol Metab. 2005 Jun;90(6):3458-65. doi: 10.1210/jc.2004-1014. Epub 2005 Mar 22.

The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7.

J Biol Chem. 2005 Apr 8;280(14):14051-6. doi: 10.1074/jbc.M500030200. Epub 2005 Feb 4.

Early human preantral follicles have relaxin and relaxin receptor (LGR7), and relaxin promotes their development.

J Clin Endocrinol Metab. 2005 Jan;90(1):516-21. doi: 10.1210/jc.2004-0130. Epub 2004 Oct 13.

Vascular endothelial growth factor: basic science and clinical progress.

Endocr Rev. 2004 Aug;25(4):581-611. doi: 10.1210/er.2003-0027.

Genetic targeting of relaxin and insulin-like factor 3 receptors in mice.

Endocrinology. 2004 Oct;145(10):4712-20. doi: 10.1210/en.2004-0515. Epub 2004 Jul 15.

Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo.

Endocrinology. 2004 Sep;145(9):4125-33. doi: 10.1210/en.2004-0209. Epub 2004 May 20.

New Insights into biological roles of relaxin and relaxin-related peptides.

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