Latent acute promyelocytic leukemia t(15;17)(q22;q12-21) and sarcoidosis: long-term cohabitation.
作者信息
Leymarie V, Galoisy A C, Falkenrodt A, Natarajan-Ame S, Dufour P, Lessard M
机构信息
Laboratory of Hematology, Hautepierre University Hospital, avenue Moliere, F-67098 Strasbourg Cedex, France.
出版信息
Eur J Intern Med. 2005 Dec;16(8):598-600. doi: 10.1016/j.ejim.2005.04.009.
PMID:16314244
Abstract
The association of sarcoidosis with hematological malignancies is a well-known phenomenon. To our knowledge, we report the first case involving sarcoidosis and acute promyelocytic leukemia (APL) t(15;17)(q22;q12-21). The major interest lies in the chronology of the two diseases: the APL demonstrated an unusual smoldering evolution, suggesting that pre-existing sarcoidosis may have a non-fortuitous immunological impact on leukemic clone proliferation.
摘要
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