Yurvati A H, Sanders S P, Dullye L J, Carney M P, Archer R L, Koro P P
Department of Cardiothoracic-Vascular Surgery, Tulsa Regional Medical Center, Oklahoma State University, OK.
South Med J. 1992 Jul;85(7):714-7. doi: 10.1097/00007611-199207000-00011.
We evaluated the antiarrhythmic response to magnesium given intravenously to 40 patients who had had elective cardiopulmonary bypass for the surgical treatment of acquired cardiac disease. All 40 patients were found to have hypomagnesemia postoperatively as defined by a serum magnesium level of less than 1.8 mg/dL. The ventricular arrhythmias of these patients were categorized by a modified Lown grade classification. Magnesium sulfate (16 mEq, [2000 mg]) was administered, and the patients were reclassified according to their rate of ventricular ectopia. All arrhythmias of a higher grade responded to the treatment with a marked reduction in ventricular ectopia and were reclassified to a lower grade. This study supports the routine administration of magnesium sulfate, at a dose of 16 mEq, in postoperative cardiac patients who are hypomagnesemic.
我们评估了静脉注射镁对40例因后天性心脏病接受择期体外循环手术治疗患者的抗心律失常反应。所有40例患者术后均出现低镁血症，定义为血清镁水平低于1.8mg/dL。这些患者的室性心律失常采用改良的洛恩分级分类法进行分类。给予硫酸镁（16mEq，[2000mg]），并根据患者室性早搏发生率重新分类。所有较高级别的心律失常对治疗均有反应，室性早搏明显减少，并重新分类为较低级别。本研究支持对术后低镁血症的心脏病患者常规给予16mEq剂量的硫酸镁。
